转化玻璃体蛋白质组学。
Translational vitreous proteomics.
机构信息
Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA; Omics Laboratory, University of Iowa, Iowa City, IA, USA.
出版信息
Proteomics Clin Appl. 2014 Apr;8(3-4):204-8. doi: 10.1002/prca.201300062. Epub 2013 Nov 4.
Abstract
The vitreous is an extracellular matrix that is still poorly understood. Although many constituents and characteristics have been previously determined, there are many attributes still being discovered. Currently, using protein arrays, MS, and bioinformatics, the vitreous provides a wealth of knowledge regarding ocular diseases and potential targets for personalized therapeutics.
摘要
玻璃体是一种细胞外基质，目前人们对其了解甚少。尽管之前已经确定了许多成分和特征，但仍有许多属性有待发现。目前，通过蛋白质阵列、MS 和生物信息学，玻璃体为眼部疾病和潜在的个体化治疗靶点提供了丰富的知识。
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