无均整滤过的强度调制屏气图像引导立体定向消融放疗（SABR）可应用于 15 分钟的治疗时段。
Flattening-filter-free intensity modulated breath-hold image-guided SABR (Stereotactic ABlative Radiotherapy) can be applied in a 15-min treatment slot.
机构信息
Department of Radiation Oncology, University Medical Center Mannheim, University of Heidelberg, Germany.
出版信息
Radiother Oncol. 2013 Dec;109(3):505-9. doi: 10.1016/j.radonc.2013.09.014. Epub 2013 Oct 12.
Hypofractionated image-guided stereotactic ablative radiotherapy (igSABR) is effective in small lung/liver lesions. Computer-assisted breath-hold reduces intrafraction motion but, as every gating/triggering strategy, reduces the duty cycle, resulting in long fraction times if combined with intensity-modulated radiotherapy (IMRT). 10 MV flattening-filter-free IMRT reduces daily fraction duration to <10 min for single doses of 5-20 Gy.
适形调强分割立体定向消融放疗（igSABR）对小的肺/肝病变有效。计算机辅助的屏气可减少分次内运动，但与每个门控/触发策略一样，会降低占空比，如果与调强放疗（IMRT）结合使用，则会导致分次时间延长。10MV 非均整滤过强射野调强放疗可将单次 5-20Gy 剂量的每日分次时间缩短至<10 分钟。
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