Department of Clinical Neurophysiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Curr Opin Pediatr. 2013 Dec;25(6):676-81. doi: 10.1097/MOP.0000000000000023.
It is easy to forget the contribution of electromyography (EMG) to the investigation of paediatric peripheral neuromuscular disease, and this review highlights its continued importance.
The discovery that Brown-Vialetto-van Leare disease, when associated with disorder of riboflavin metabolism, may be treatable has raised awareness of the importance of EMG for its early detection. Unexpected discovery of motor neuronopathy, which may be useful for the definition of the phenotype of several conditions, now has an added significance. The investigation of disorders of peripheral nerve cannot proceed without nerve conduction studies but particular interest has been shown in its role in the management of obstetric brachial plexus palsy, with investigation within 1 month now recommended. The key role of neurophysiology in identifying abnormalities of the neuromuscular junction, and therefore leading investigators to a diagnosis of myasthenia, is once again highlighted. EMG in muscle disease continues to have a role, particularly when identifying myotonia.
Paediatric EMG, while a daunting technical challenge to some practitioners, remains a valuable investigative tool for the specialists in paediatric neuromuscular disorders and will continue to deliver important diagnostic information, often as quickly and accurately as other more recent innovations.
人们很容易忘记肌电图（EMG）对儿科周围神经肌肉疾病研究的贡献，而本篇综述强调了其持续的重要性。
当发现与核黄素代谢紊乱相关的 Brown-Vialetto-Van Laere 病可能具有可治疗性时，人们开始意识到 EMG 对早期发现该病的重要性。现在，运动神经元病的意外发现可能对几种疾病表型的定义有用，其意义有所增加。如果没有神经传导研究，外周神经疾病的研究就无法进行，但人们对其在产科臂丛神经病管理中的作用特别感兴趣，现在建议在 1 个月内进行检查。神经生理学在识别神经肌肉接头异常方面的关键作用，因此引导研究人员做出肌无力的诊断，再次得到强调。EMG 在肌肉疾病中的作用仍然存在，特别是在识别肌强直时。
儿科 EMG 虽然对一些从业者来说是一项令人生畏的技术挑战，但仍然是儿科神经肌肉疾病专家的宝贵研究工具，它将继续提供重要的诊断信息，其速度和准确性往往与其他更新的创新技术一样。
