不同运动习惯个体对急性运动的循环脑源性神经营养因子反应不同。
Different circulating brain-derived neurotrophic factor responses to acute exercise between physically active and sedentary subjects.
机构信息
Institute of Health Science, Kyushu University, Kasuga , Fukuoka, Japan.
出版信息
J Sports Sci Med. 2012 Mar 1;11(1):83-8. eCollection 2012.
UNLABELLED
Although circulating brain-derived neurotrophic factor (BDNF) level is affected by both acute and chronic physical activity, the interaction of acute and chronic physical activity was still unclear. In this study, we compared the serum and plasma BDNF responses to maximal and submaximal acute exercises between physically active and sedentary subjects. Eight active and 8 sedentary female subjects participated in the present study. Both groups performed 3 exercise tests with different intensities, i.e. 100% (maximal), 60% (moderate) and 40% (low) of their peak oxygen uptake. In each exercise test, blood samples were taken at the baseline and immediately, 30 and 60 min after the test. The serum BDNF concentration was found to significantly increase immediately after maximal and moderate exercise tests in both groups. In maximal exercise test, the pattern of change in the serum BDNF concentration was different between the groups. While the serum BDNF level for the sedentary group returned to the baseline level during the recovery phase, the BDNF levels for the active group decreased below the baseline level after the maximal exercise test. No group differences were observed in the pattern of plasma BDNF change for all exercise tests. These findings suggest that regular exercise facilitates the utilization of circulating BDNF during and/or after acute exercise with maximal intensity.
KEY POINTS
In maximal exercise test, the pattern of change in the serum BDNF concentration was different between the groups.While the serum BDNF level for the sedentary group returned to the baseline level during the recovery phase, the BDNF levels for the active group decreased below the baseline level after the maximal exercise test.No group differences were observed in the pattern of serum BDNF change for moderate or low exercise tests.No group differences were observed in the pattern of plasma BDNF change for all exercise tests.
未加标签
虽然循环脑源性神经营养因子（BDNF）水平受到急性和慢性体力活动的影响，但急性和慢性体力活动的相互作用仍不清楚。在这项研究中，我们比较了活跃和久坐的受试者在最大和亚最大急性运动中血清和血浆 BDNF 反应。8 名活跃和 8 名久坐的女性受试者参加了本研究。两组都进行了 3 项不同强度的运动测试，即 100%（最大）、60%（适度）和 40%（低）的峰值摄氧量。在每项运动测试中，在基线和测试后立即、30 分钟和 60 分钟取血样。发现血清 BDNF 浓度在两组的最大和适度运动测试后立即显著增加。在最大运动测试中，两组之间血清 BDNF 浓度变化的模式不同。虽然久坐组的血清 BDNF 水平在恢复期恢复到基线水平，但活跃组的 BDNF 水平在最大运动测试后降至基线以下。在所有运动测试中，血浆 BDNF 变化模式在两组之间没有差异。这些发现表明，定期运动有助于在最大强度的急性运动期间和/或之后利用循环 BDNF。
关键点
在最大运动测试中，两组之间血清 BDNF 浓度变化的模式不同。虽然久坐组的血清 BDNF 水平在恢复期恢复到基线水平，但活跃组的 BDNF 水平在最大运动测试后降至基线以下。在适度或低强度运动测试中，血清 BDNF 变化模式在两组之间没有差异。在所有运动测试中，血浆 BDNF 变化模式在两组之间没有差异。
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