Javed Fawad, Romanos Georgios E
1 Eng. A.B. Research Chair for Growth Factors and Bone Regeneration, 3D Imaging and Biomechanical Laboratory, College of Applied Medical Sciences, King Saud University , Riyadh, Saudi Arabia .
Photomed Laser Surg. 2013 Nov;31(11):512-8. doi: 10.1089/pho.2012.3329. Epub 2013 Oct 19.
The aim of this study was to assess whether or not photodynamic therapy enhanced standard antibacterial therapy in dentistry.
Photodynamic therapy when used as an adjunct to conventional periodontal therapy kills more bacteria than when conventional periodontal therapy is used alone.
To address the focused question, "Does photodynamic therapy enhance killing of oral bacteria?" PubMed/MEDLINE(®) and Google Scholar databases were explored. Original human and experimental studies and studies using photodynamic therapy for killing oral bacteria were included. Letters to the Editor, historic reviews, and unpublished data were excluded.
Photodynamic therapy significantly reduces periodontopathogenic bacteria including Aggregatibacter actinomycetemcomitans, Prevotella intermedia, and Porphyromonas gingivalis. Photodynamic therapy kills cariogenic bacteria (such as Streptococcus mutans and Streptococcus sanguis), bacteria associated with infected root canals, and those associated with periimplantitis.
Photodynamic therapy, when used as an adjunct to conventional oral disinfection protocols, enhances standard antibacterial therapy in dentistry.
本研究旨在评估光动力疗法是否能增强牙科中的标准抗菌治疗。
光动力疗法作为传统牙周治疗的辅助手段时，比单独使用传统牙周治疗能杀死更多细菌。
为解决核心问题“光动力疗法能否增强对口腔细菌的杀灭作用？”，我们检索了PubMed/MEDLINE(®)和谷歌学术数据库。纳入了关于人类和实验的原始研究以及使用光动力疗法杀灭口腔细菌的研究。排除了致编辑信、历史综述和未发表的数据。
光动力疗法能显著减少牙周病原菌，包括伴放线聚集杆菌、中间普氏菌和牙龈卟啉单胞菌。光动力疗法能杀死致龋菌（如变形链球菌和血链球菌）、与感染根管相关的细菌以及与种植体周围炎相关的细菌。
光动力疗法作为传统口腔消毒方案的辅助手段时，能增强牙科中的标准抗菌治疗。
