Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.
J Am Chem Soc. 2013 Nov 6;135(44):16352-5. doi: 10.1021/ja409223a. Epub 2013 Oct 24.
An amide-derived NNN-Ru(II) hydride complex catalyzes oxidant-free, acceptorless, and chemoselective dehydrogenation of primary and secondary amines to the corresponding nitriles and imines with liberation of dihydrogen. The catalyst system tolerates oxidizable functionality and is selective for the dehydrogenation of primary amines (-CH2NH2) in the presence of amines without α-CH hydrogens.
酰胺衍生的 NNN-Ru(II)氢化物配合物能够在无氧化剂、无受体和化学选择性的条件下，催化伯胺和仲胺脱氢生成相应的腈和亚胺，并释放氢气。该催化剂体系对可氧化官能团具有耐受性，并且在没有α-CH 氢的情况下，能够选择性地催化伯胺（-CH2NH2）脱氢。
