猫爪草皂苷和多糖对人胃癌BGC823细胞的抑制作用。
Inhibitory effect of saponins and polysaccharides from Radix ranunculi ternati on human gastric cancer BGC823 cells.
作者信息
Niu Lidan, Zhou Yingfeng, Sun Bing, Hu Junling, Kong Lingyu, Duan Sufang
机构信息
The First Affiliated Hospital of Xinxiang Medical University.
出版信息
Afr J Tradit Complement Altern Med. 2013 Apr 12;10(3):561-6. doi: 10.4314/ajtcam.v10i3.26. eCollection 2013.
Abstract
The effects of different Radix ranunculi ternati extracts on human gastric cancer BGC823 cells were investigated, different methods were used to extract the saponins and polysaccharides from Radix ranunculi ternati, and MTT assay and colony formation assay were used to observe the effects of saponins and polysaccharides from Radix ranunculi ternati on in-vitro cultured human gastric cancer BGC823 cells. The results found that the saponins and polysaccharides from Radix Ranunculi Ternati had certain effects on both the growth and colony formation of human gastric cancer BGC823 cells, while improving the immune function of normal mice, of which saponins had more significant effects than polysaccharides.
摘要
研究了不同的猫爪草提取物对人胃癌BGC823细胞的影响，采用不同方法从猫爪草中提取皂苷和多糖，并运用MTT法和集落形成试验观察猫爪草皂苷和多糖对体外培养的人胃癌BGC823细胞的影响。结果发现，猫爪草皂苷和多糖对人胃癌BGC823细胞的生长和集落形成均有一定影响，同时可提高正常小鼠的免疫功能，其中皂苷的作用比多糖更为显著。
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