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本文引用的文献

1
Longitudinal effects of prenatal cocaine use on mother-child interactions at ages 3 and 5 years.产前可卡因使用对 3 岁和 5 岁母婴互动的纵向影响。
J Dev Behav Pediatr. 2012 Jan;33(1):32-41. doi: 10.1097/DBP.0b013e31823968ab.
2
Deviant ERP response to spoken non-words among adolescents exposed to cocaine in utero.宫内暴露于可卡因的青少年对口语非词的异常 ERP 反应。
Brain Lang. 2012 Mar;120(3):209-16. doi: 10.1016/j.bandl.2011.09.002. Epub 2011 Oct 5.
3
Concurrent and construct validity of oral language measures with school-age children with specific language impairment.特定语言障碍学龄儿童口语语言测量的同时效度和构念效度。
J Speech Lang Hear Res. 2011 Dec;54(6):1597-608. doi: 10.1044/1092-4388(2011/10-0213). Epub 2011 Sep 19.
4
Adolescents with and without gestational cocaine exposure: Longitudinal analysis of inhibitory control, memory and receptive language.有和没有妊娠期可卡因暴露的青少年:抑制控制、记忆和接受性语言的纵向分析。
Neurotoxicol Teratol. 2011 Jan-Feb;33(1):36-46. doi: 10.1016/j.ntt.2010.08.004.
5
Estimated effects of in utero cocaine exposure on language development through early adolescence.胎儿期可卡因暴露对语言发展的影响估计到青少年早期。
Neurotoxicol Teratol. 2011 Jan-Feb;33(1):25-35. doi: 10.1016/j.ntt.2010.07.001.
6
Prenatal and postnatal cocaine exposure predict teen cocaine use.产前和产后可卡因暴露可预测青少年可卡因使用。
Neurotoxicol Teratol. 2011 Jan-Feb;33(1):110-9. doi: 10.1016/j.ntt.2010.06.011. Epub 2010 Jul 6.
7
The effects of prenatal cocaine on language development at 10 years of age.产前可卡因对 10 岁儿童语言发展的影响。
Neurotoxicol Teratol. 2011 Jan-Feb;33(1):17-24. doi: 10.1016/j.ntt.2010.06.006. Epub 2010 Jun 30.
8
Children of addicted women.成瘾女性的子女。
J Addict Dis. 2010 Apr;29(2):259-76. doi: 10.1080/10550881003684921.
9
A review of the effects of prenatal cocaine exposure among school-aged children.对学龄儿童产前可卡因暴露影响的综述。
Pediatrics. 2010 Mar;125(3):554-65. doi: 10.1542/peds.2009-0637. Epub 2010 Feb 8.
10
Prenatal cocaine exposure: drug and environmental effects at 9 years.产前可卡因暴露:9岁时的药物及环境影响
J Pediatr. 2008 Jul;153(1):105-11. doi: 10.1016/j.jpeds.2008.01.001. Epub 2008 Mar 6.

儿童产前暴露于可卡因后 12 年的语言结果。

Language outcomes at 12 years for children exposed prenatally to cocaine.

机构信息

Correspondence to Barbara A. Lewis:

出版信息

J Speech Lang Hear Res. 2013 Oct;56(5):1662-76. doi: 10.1044/1092-4388(2013/12-0119).

DOI:10.1044/1092-4388(2013/12-0119)
PMID:24149136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4131682/
Abstract

PURPOSE

In this study, the authors aimed to examine the long-term effects of prenatal cocaine exposure (PCE) on the language development of 12-year-old children using a prospective design, controlling for confounding prenatal drug exposure and environmental factors.

METHOD

Children who were exposed to cocaine in utero (PCE; n = 183) and children who were not exposed to cocaine (i.e., no cocaine exposure [NCE]; n = 181) were followed prospectively from birth to 12 years of age and were compared on language subtests of the Test of Language Development-Intermediate, Third Edition ( Hammill & Newcomer, 1997b), and phonological processing as measured by the Comprehensive Test of Phonological Processing ( Wagner & Torgesen, 1999). The authors evaluated the relationship of PCE to language development through a multivariate analysis of covariance and regression analyses while controlling for confounders.

RESULTS

Results show that PCE has small effects on specific aspects of language, including syntax and phonological processing. The caregiver variables of lower maternal vocabulary, more psychological symptoms, and a poorer home environment also had consistent effects on language and phonological processing scores.

CONCLUSIONS

These findings suggest that PCE continues to have small, subtle effects on specific aspects of language at age 12 years. Phonological processing skills were significantly related to the reading outcomes of letter-word identification, reading fluency, and reading comprehension, indicating that PCE also has small but lasting effects on the language skills that are related to later literacy skills.

摘要

目的

本研究旨在采用前瞻性设计,控制混杂的产前药物暴露和环境因素,检验产前可卡因暴露(PCE)对 12 岁儿童语言发展的长期影响。

方法

本研究对 183 名宫内暴露于可卡因的儿童(PCE 组)和 181 名未暴露于可卡因的儿童(即无可卡因暴露 [NCE] 组)进行了前瞻性随访,从出生到 12 岁,并比较了他们在语言发展测试-中级(第三版)(Hammill & Newcomer,1997b)的语言子测试和语音处理上的差异,语音处理通过综合语音处理测试(Wagner & Torgesen,1999)进行测量。作者通过协方差分析和回归分析评估了 PCE 与语言发展的关系,同时控制了混杂因素。

结果

结果表明,PCE 对语言的特定方面(包括语法和语音处理)有较小的影响。照顾者的变量(如母亲词汇量较低、更多的心理症状和较差的家庭环境)也对语言和语音处理分数有一致的影响。

结论

这些发现表明,PCE 对 12 岁儿童语言的特定方面仍有持续的、微小的影响。语音处理技能与字母词识别、阅读流畅性和阅读理解的阅读成绩显著相关,表明 PCE 对与后续读写能力相关的语言技能也有微小但持久的影响。