Hogeman P H, Veerman A J, Philippus E, Huismans D R, van Zantwijk C H, Bezemer P D
Acta Haematol. 1985;73(4):196-200. doi: 10.1159/000206327.
The density of HLA determinants on the cell surface was studied in relation to HLA capping in childhood acute lymphoblastic leukemia (ALL). Analysis was performed with flow cytometry (FACS) and a subjective labeling score. These two methods gave comparable results. In T-ALL high percentages of capped cells were related to low numbers of HLA determinants. In c-ALL we found the opposite. This study shows that capping capacity and number of HLA determinants in childhood ALL are inversely related.
针对儿童急性淋巴细胞白血病（ALL）中HLA决定簇在细胞表面的密度与HLA封帽现象的关系展开了研究。采用流式细胞术（FACS）和主观标记评分法进行分析。这两种方法得出了可比的结果。在T-ALL中，高比例的封帽细胞与低数量的HLA决定簇相关。在c-ALL中我们发现情况相反。本研究表明，儿童ALL中的封帽能力与HLA决定簇数量呈负相关。
