Stahl M, Ruhstaller T
Klinik für Internistische Onkologie und Hämatologie, Kliniken Essen-Mitte, Henricistr. 92, 45136 , Essen, Deutschland,
Internist (Berl). 2014 Jan;55(1):7-8, 10-4. doi: 10.1007/s00108-013-3315-7.
Oesophageal carcinoma reflects a tumor entity which can be optimally treated with multimodal therapy. Early lymphatic spread and late symptoms lead to mostly advanced tumors at primary diagnosis, which means that they can not be cured by surgery alone. On the other hand these tumors show high sensitivity towards chemo- and radiotherapy. Chemoradiotherapy followed by surgery (trimodal therapy) is considered an international standard of care for operable patients. Definitive chemoradiotherapy or the flexible concept of chemoradiotherapy with optional salvage surgery can be curative options for patients with increased operative risk.
食管癌是一种可通过多模式治疗实现最佳治疗效果的肿瘤实体。早期淋巴转移和出现较晚的症状导致大多数肿瘤在初次诊断时已处于晚期，这意味着仅靠手术无法治愈。另一方面，这些肿瘤对化疗和放疗表现出高度敏感性。化疗联合放疗后再进行手术（三联疗法）被认为是适合可手术患者的国际标准治疗方案。对于手术风险增加的患者，根治性放化疗或采用灵活的放化疗方案并选择性进行挽救性手术可能是治愈性选择。
