Tintelnot K
Konsiliarlabor für Kryptokokkose, Scedosporiose und importierte Systemmykosen, Robert Koch-Institut, Nordufer 20, 13353, Berlin, Deutschland,
Pathologe. 2013 Nov;34(6):519-27. doi: 10.1007/s00292-013-1828-4.
The differential diagnosis of yeasts or yeast-like organisms includes a series of imported and domestic fungal pathogens. The spectrum of fungal pathogens involves dimorphic fungi which may cause deep mycoses in healthy people as well as opportunistic fungi, which require predisposing factors for infection, e.g. immunosuppression or a trauma. The histology is sometimes unambiguous; however, frequently there is a great similarity between diverse fungal infections in tissues and the diagnostically decisive criteria are only obvious in a few pathogens. In addition to a classical culture technique in doubtful cases molecular biological or serological methods are necessary to confirm any suspected pathogen diagnosis.
酵母或酵母样生物体的鉴别诊断包括一系列进口和国产真菌病原体。真菌病原体的范围涉及可能在健康人群中引起深部真菌病的双相真菌以及需要感染诱发因素（如免疫抑制或创伤）的机会性真菌。组织学有时并不明确；然而，不同真菌感染在组织中常常有很大的相似性，诊断的决定性标准仅在少数病原体中明显。除了在疑难病例中采用经典培养技术外，还需要分子生物学或血清学方法来确诊任何疑似病原体诊断。
