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加拿大南亚裔儿童哮喘的患病率。

The prevalence of asthma in Canadian children of South Asian descent.

机构信息

Desiderius School of Medicine, Erasmus, MC, Rotterdam, The Netherlands.

出版信息

Pediatr Pulmonol. 2014 Jan;49(1):43-8. doi: 10.1002/ppul.22907. Epub 2013 Oct 24.

Abstract

BACKGROUND

Asthma is the most common disease in childhood. The prevalence of asthma is known to vary greatly between and within countries and among different ethnic groups. In this study, we aimed to determine the prevalence of asthma and wheezing symptoms in South Asian children living in Canada.

METHODS

In a cross sectional study, data from the Phase III International Study on Asthma and Allergies in Childhood (ISAAC) were analyzed. A surname algorithm to determine South Asian ethnic descent was used. Prevalence was calculated and compared to non-South Asian children from the same survey and to the reported prevalence from the Indian subcontinent ISAAC III survey for children ages 6-9 and 13-16.

RESULTS

The prevalence of asthma and wheezing did not differ between children of South Asian descent and non-South Asians living Canada. When compared to the children living in India, the prevalence of asthma, wheeze, and exercise induced wheeze was significantly higher in the South Asian children living in Canada. Higher body mass index of the child, parental smoking, and pet ownership were strongly associated with asthma and wheeze.

CONCLUSIONS

In contrast to other studies these data suggest that South Asian children living in Canada have a similar asthma prevalence to non-South Asian children; both of whom had higher asthma prevalence compared with children residing in South Asia. This suggests that environmental and social factors play a role in asthma prevalence. Risk factors for asthma in children of South Asian descent living in Canada are similar to those of the overall population.

摘要

背景

哮喘是儿童中最常见的疾病。已知哮喘的患病率在国家之间、国家内部和不同种族群体之间存在很大差异。在这项研究中,我们旨在确定居住在加拿大的南亚儿童中哮喘和喘息症状的患病率。

方法

在一项横断面研究中,分析了第三阶段国际儿童哮喘和过敏研究(ISAAC)的数据。使用姓氏算法来确定南亚种族血统。计算患病率并将其与来自同一调查的非南亚儿童以及来自印度次大陆 ISAAC III 调查的报告患病率进行比较,该调查针对 6-9 岁和 13-16 岁的儿童。

结果

南亚血统的儿童和居住在加拿大的非南亚儿童的哮喘和喘息患病率没有差异。与居住在印度的儿童相比,居住在加拿大的南亚儿童的哮喘、喘息和运动诱发喘息的患病率明显更高。儿童的体重指数较高、父母吸烟和养宠物与哮喘和喘息密切相关。

结论

与其他研究不同,这些数据表明,居住在加拿大的南亚儿童的哮喘患病率与非南亚儿童相似;与居住在南亚的儿童相比,他们的哮喘患病率都更高。这表明环境和社会因素在哮喘患病率中起作用。居住在加拿大的南亚裔儿童的哮喘风险因素与总体人群相似。

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