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Carbon nanotubes: present and future commercial applications.碳纳米管：当前和未来的商业应用。
Science. 2013 Feb 1;339(6119):535-9. doi: 10.1126/science.1222453.
2
Metabolic toxicity screening using electrochemiluminescence arrays coupled with enzyme-DNA biocolloid reactors and liquid chromatography-mass spectrometry.基于电化学发光阵列与酶-DNA 生物胶粒反应器和液相色谱-质谱联用的代谢毒性筛选
Annu Rev Anal Chem (Palo Alto Calif). 2012;5(1):79-105. doi: 10.1146/annurev.anchem.111808.073659. Epub 2012 Apr 5.
3
[Myeloperoxidase-induced biodegradation of single-walled carbon nanotubes is mediated by hypochlorite].[髓过氧化物酶诱导的单壁碳纳米管生物降解由次氯酸盐介导]
Bioorg Khim. 2011 Jul-Aug;37(4):510-21. doi: 10.1134/s1068162011040157.
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Nano delivers big: designing molecular missiles for cancer therapeutics.纳米传递大：设计用于癌症治疗的分子导弹。
Pharmaceutics. 2011;3(1):34-52. doi: 10.3390/pharmaceutics3010034.
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Advancement in carbon nanotubes: basics, biomedical applications and toxicity.碳纳米管的研究进展：基础、生物医学应用及毒性。
J Pharm Pharmacol. 2011 Feb;63(2):141-63. doi: 10.1111/j.2042-7158.2010.01167.x. Epub 2010 Nov 16.
6
Distribution and clearance of PEG-single-walled carbon nanotube cancer drug delivery vehicles in mice.聚乙二醇-单壁碳纳米管癌症药物输送载体在小鼠体内的分布和清除。
Nanomedicine (Lond). 2010 Dec;5(10):1535-46. doi: 10.2217/nnm.10.90.
7
Oxidative biodegradation of single- and multi-walled carbon nanotubes.单壁和多壁碳纳米管的氧化生物降解。
Nanoscale. 2011 Mar;3(3):893-6. doi: 10.1039/c0nr00779j. Epub 2010 Nov 29.
8
Mechanisms and measurements of nanomaterial-induced oxidative damage to DNA.纳米材料诱导 DNA 氧化损伤的机制与检测。
Anal Bioanal Chem. 2010 Sep;398(2):613-50. doi: 10.1007/s00216-010-3881-7. Epub 2010 Jun 22.
9
Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation.中性粒细胞髓过氧化物酶降解的碳纳米管可引起较少的肺部炎症。
Nat Nanotechnol. 2010 May;5(5):354-9. doi: 10.1038/nnano.2010.44. Epub 2010 Apr 4.
10
Biodurability of Single-Walled Carbon Nanotubes Depends on Surface Functionalization.单壁碳纳米管的生物耐久性取决于表面功能化。
Carbon N Y. 2010 Jun 1;48(7):1961-1969. doi: 10.1016/j.carbon.2010.02.002.

评估酶氧化单壁碳纳米管造成的DNA损伤。

Assessing DNA Damage from Enzyme-Oxidized Single-Walled Carbon Nanotubes.

作者信息

Pan Shenmin, Sardesai Naimish P, Liu Hongyun, Rusling James F

机构信息

Department of Chemistry, University of Connecticut.

出版信息

Toxicol Res (Camb). 2013 Nov 1;2(6):375-378. doi: 10.1039/C3TX50022E.

DOI:10.1039/C3TX50022E
PMID:24159372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3804378/
Abstract

Peroxidase enzyme digests of oxidized single-wall carbon nanotubes (SWCNT) were shown to damage DNA in potentially genotoxic reactions for the first time using an electro-optical array with and without metabolic activation.

摘要

首次使用带和不带代谢活化的电光阵列证明，氧化单壁碳纳米管（SWCNT）的过氧化物酶消化物在潜在的基因毒性反应中会损伤DNA。