哥伦比亚复发性呼吸道乳头瘤病的临床特征和 HPV 型别。
Clinical characteristics and HPV type in recurrent respiratory papillomatosis in Colombia.
机构信息
Centro Médico Imbanaco, Cali, Colombia.
出版信息
Salud Publica Mex. 2013 Aug;55(4):416-20. doi: 10.21149/spm.v55i4.7226.
OBJECTIVE
Describe factors associated with aggressive forms of recurrent respiratory papillomatosis (RRP).
MATERIALS AND METHODS
One hundred eighty-nine RRP cases diagnosed between 1985 and 2009 were identified in pathological records. HPV was detected by the SPF-10 method with broad spectrum primers, (version 1).
RESULTS
113 patients had only one surgery (less aggressive) and 76, two or more interventions (more aggressive). The likelihood of aggressive lesions decreased with increasing age at diagnosis and HPV-11 was associated with no significant increase in the risk of aggressiveness.
CONCLUSIONS
The age at diagnosis was the main determinant of RRP aggressiveness.
目的
描述与复发性呼吸道乳头瘤病（RRP）侵袭性形式相关的因素。
材料和方法
在病理记录中，确定了 1985 年至 2009 年间诊断出的 189 例 RRP 病例。HPV 采用广谱引物的 SPF-10 方法（第 1 版）进行检测。
结果
113 例患者仅接受一次手术（侵袭性较小），76 例患者接受两次或更多次干预（侵袭性较大）。侵袭性病变的可能性随着诊断时年龄的增加而降低，HPV-11 与侵袭性增加的风险无显著相关性。
结论
诊断时的年龄是 RRP 侵袭性的主要决定因素。
Zotero 插件