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本文引用的文献

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Unintentional prescription opioid-related overdose deaths: description of decedents by next of kin or best contact, Utah, 2008-2009.非故意处方类阿片类药物相关过量死亡:犹他州 2008-2009 年近亲或最佳联系人描述的死者。
J Gen Intern Med. 2013 Apr;28(4):522-9. doi: 10.1007/s11606-012-2225-z. Epub 2012 Oct 16.
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Clinical policy: critical issues in the prescribing of opioids for adult patients in the emergency department.临床政策:急诊科成年患者阿片类药物处方的关键问题
Ann Emerg Med. 2012 Oct;60(4):499-525. doi: 10.1016/j.annemergmed.2012.06.013.
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Medical and nonmedical use of prescription opioids among high school seniors in the United States.美国高中高年级学生中处方阿片类药物的医疗和非医疗用途。
Arch Pediatr Adolesc Med. 2012 Sep 1;166(9):797-802. doi: 10.1001/archpediatrics.2012.85.
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Extramedical use of prescription pain relievers by youth aged 12 to 21 years in the United States: national estimates by age and by year.美国12至21岁青少年对处方止痛药的非医疗用途:按年龄和年份的全国估计数。
Arch Pediatr Adolesc Med. 2012 Sep 1;166(9):803-7. doi: 10.1001/archpediatrics.2012.209.
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CDC grand rounds: prescription drug overdoses - a U.S. epidemic.疾病预防控制中心例会:处方药物滥用——美国的一大流行病。
MMWR Morb Mortal Wkly Rep. 2012 Jan 13;61(1):10-3.
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Vital signs: overdoses of prescription opioid pain relievers---United States, 1999--2008.生命体征:1999 年至 2008 年美国处方类阿片类止痛药过量。
MMWR Morb Mortal Wkly Rep. 2011 Nov 4;60(43):1487-92.
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Early Age-of-onset Drinking Predicts Prescription Drug Misuse Among Teenagers and Young Adults: Results from a National Survey.早发性饮酒预测青少年和年轻成年人的处方药物滥用:一项全国性调查的结果。
J Addict Med. 2008 Mar;2(1):22-30. doi: 10.1097/ADM.0b013e3181565e14.
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Project Lazarus: community-based overdose prevention in rural North Carolina. Lazarus 项目:北卡罗来纳州农村地区的基于社区的过量预防。
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Opioid dose and drug-related mortality in patients with nonmalignant pain.非恶性疼痛患者的阿片类药物剂量与药物相关死亡率
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Association between opioid prescribing patterns and opioid overdose-related deaths.阿片类药物处方模式与阿片类药物过量相关死亡之间的关联。
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非医疗处方类阿片和镇静剂在急诊室青少年中的使用情况。

Nonmedical prescription opioid and sedative use among adolescents in the emergency department.

机构信息

Harborview Medical Center, 325 9th Ave, Box 359702, Seattle, WA 98104-2499.

出版信息

Pediatrics. 2013 Nov;132(5):825-32. doi: 10.1542/peds.2013-0721. Epub 2013 Oct 28.

DOI:10.1542/peds.2013-0721
PMID:24167166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3813392/
Abstract

OBJECTIVES

Nonmedical prescription opiate use (NPOU) and nonmedical prescription sedative use (NPSU) are serious public health concerns. The objectives of this study were to determine the prevalence and emergency department (ED) visit characteristics and other correlates associated with past-year NPOU and NPSU among adolescents and young adults using the ED.

METHODS

Participants aged 14 to 20 presenting to the ED at the University of Michigan Medical Center between September 2010 and September 2011 were systematically recruited. A computerized self-report screening survey with validated items measuring past-year NPOU, NPSU, substance use, and violence was delivered to participants, and a retrospective chart review was performed.

RESULTS

Of the 2135 participants (86.0% response rate), 222 (10.4%) reported either NPOU or NPSU. Among the 185 (8.7%) participants that reported NPOU, 14.6% had a current home prescription for an opioid and among the 115 (5.4%) with NPSU, 12.3% had a current home prescription for a sedative. After controlling for demographics (age, gender, race, public assistance), correlates of NPOU or NPSU included other substance use, and drinking and driving or riding with a drinking driver. Additional correlates of NPOU included receiving an intravenous opioid in the ED and for NPSU, dating violence, presenting to the ED for a noninjury complaint, and previous ED visit in the past year.

CONCLUSIONS

Nearly 1 in 10 young people who use the ED for care report NPOU or NPSU, and only 12.3% and 14.6% report having current home prescriptions for sedatives and opioids. The ED represents a key location for screening and intervention efforts.

摘要

目的

非医疗目的使用鸦片类药物(NPOU)和非医疗目的使用镇静剂(NPSU)是严重的公共卫生问题。本研究的目的是确定在使用急诊室(ED)的青少年和年轻成年人中,过去一年 NPOU 和 NPSU 的流行率以及与 ED 就诊特征和其他相关因素。

方法

2010 年 9 月至 2011 年 9 月期间,在密歇根大学医疗中心的 ED 接受系统招募的年龄在 14 至 20 岁的参与者。向参与者提供了一份带有经过验证的项目的计算机化自我报告筛查调查,以测量过去一年的 NPOU、NPSU、物质使用和暴力情况,并进行了回顾性图表审查。

结果

在 2135 名参与者中(86.0%的回应率),222 名(10.4%)报告了 NPOU 或 NPSU。在 185 名(8.7%)报告 NPOU 的参与者中,14.6%有当前家庭开出的阿片类药物处方,在 115 名(5.4%)有 NPSU 的参与者中,12.3%有当前家庭开出的镇静剂处方。在控制人口统计学因素(年龄、性别、种族、公共援助)后,NPOU 或 NPSU 的相关因素包括其他物质使用、饮酒和酒后驾车或与饮酒司机一起乘车。NPOU 的其他相关因素包括在 ED 接受静脉内阿片类药物治疗,以及 NPSU 包括约会暴力、因非伤害性投诉就诊 ED 和过去一年的 ED 就诊。

结论

近 10%的在 ED 接受治疗的年轻人报告 NPOU 或 NPSU,只有 12.3%和 14.6%报告有当前家庭开出的镇静剂和阿片类药物处方。ED 代表了筛查和干预措施的重要场所。