Fund for the Replacement of Animals in Medical Experiments (FRAME), Nottingham, UK.
Altern Lab Anim. 2013 Sep;41(4):313-9. doi: 10.1177/026119291304100407.
The Annual Statistics of Scientific Procedures on Living Animals Great Britain 2012 reveal that the level of animal experimentation in Great Britain continues to rise, with just over 4.1 million procedures being started in that year. Despite the previous year's indication that the dominance of the production and use of genetically-altered (GA, i.e. genetically-modified animals plus animals with harmful genetic defects) animal might be abating, it returned with a vengeance in 2012. Breeding increased from 43% to 48% of all procedures, and GA animals were involved in 59% of all the procedures. Indeed, if the breeding of these animals were removed from the statistics, the total number of procedures would actually decline by 2%. In order to honour their pledge to reduce animal use in science, the Coalition Government will have to address this issue. The general trends in the species used, and the numbers and types of procedures, are also reviewed. Finally, forthcoming changes to the statistics are discussed.
《2012 年英国活体动物科学程序年度统计》显示，英国的动物实验水平持续上升，仅在该年就有超过 410 万例实验开始。尽管前一年的统计数据显示，基因改造（GA，即基因修饰动物加上具有有害遗传缺陷的动物）动物的生产和使用可能正在减少，但 2012 年它们又卷土重来。繁殖在所有实验中的比例从 43%增加到 48%，GA 动物占所有实验的 59%。事实上，如果从统计数据中去除这些动物的繁殖，实验总数实际上将减少 2%。为了履行减少科学领域动物使用的承诺，联合政府将不得不解决这个问题。文中还审查了所用物种的总体趋势，以及实验的数量和类型。最后，还讨论了即将进行的统计数据变更。
