2009 - 2012年未标注的法国抗生素指南对7家儿科急诊科急性呼吸道感染抗生素处方的影响
Impact of unlabeled French antibiotic guidelines on antibiotic prescriptions for acute respiratory tract infections in 7 Pediatric Emergency Departments, 2009-2012.
作者信息
Angoulvant François, Pereira Miguel, Perreaux Francis, Soussan Valerie, Pham Luu-Ly, Trieu Thanh-Van, Cojocaru Bogdan, Guedj Romain, Cohen Robert, Alberti Corinne, Gajdos Vincent
机构信息
From the *Hôpitaux de Paris (APHP), Pediatric Emergency Department, Hôpital Robert Debré and Université Paris 7 Denis Diderot, Paris; †Inserm, CESP Centre for Research in Epidemiology and Population Health, U1018, Reproduction and Child Development Team, Villejuif; ‡Hôpitaux de Paris (APHP), Pediatric Department, Hôpital Antoine Béclère and Université Paris 11, Clamart; §Hôpitaux de Paris (APHP), Pediatric Department, Hôpital Ambroise Paré and Université Versailles-Saint-Quentin-en-Yvelines, Boulogne; ¶Hôpitaux de Paris (APHP), Pediatric Department, Hôpital Bicêtre and Université Paris 11, Kremlin-Bicêtre; ‖Hôpitaux de Paris (APHP), Pediatric Department, Hôpital Jean Verdier and Université Paris 13, Bondy; ††Hôpitaux de Paris (APHP), Pediatric Department, Hôpital Louis Mourier and Université Paris 7 Denis Diderot, Colombes; ‡‡Hôpitaux de Paris (APHP), Pediatric Emergency Department, Hôpital Armand Trousseau and Université Paris 6 Descartes, Paris; §§Pediatric Department, Centre Hospitalier Intercommunal, Créteil; and ¶¶Hôpitaux de Paris (APHP), Clinical Epidemiologic Unit and INSERM CIE-5, Hôpital Robert Debré and Université Paris 7 Denis Diderot, Paris, France.
出版信息
Pediatr Infect Dis J. 2014 Mar;33(3):330-3. doi: 10.1097/INF.0000000000000125.
From November 2009 to October 2012, implementation of guidelines, unlabeled by the French Agency of Health Products, changed the categories of antibiotics prescribed for acute respiratory tract infections in 7 pediatric emergency departments. During the study, 36,413 acute respiratory tract infections-related antibiotic prescriptions were prescribed. Amoxicillin prescriptions rose from 30.0% to 84.7%, while amoxicillin-clavulanate and cefpodoxime prescriptions decreased to 10.2% and 2.5%, respectively.
2009年11月至2012年10月，在未获法国卫生产品管理局标注的情况下实施的指南，改变了7家儿科急诊科针对急性呼吸道感染所开具的抗生素类别。在研究期间，共开具了36413份与急性呼吸道感染相关的抗生素处方。阿莫西林的处方比例从30.0%升至84.7%，而阿莫西林-克拉维酸和头孢泊肟的处方比例分别降至10.2%和2.5%。
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