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主动脉内球囊反搏在急性心肌梗死中的应用:老而新的适应证。

Intra-aortic balloon counterpulsation in acute myocardial infarction: old and emerging indications.

机构信息

Department of Cardiology, Catharina Hospital Eindhoven, Michelangelolaan 2, 5623 EJ, Eindhoven, the Netherlands.

出版信息

Neth Heart J. 2013 Dec;21(12):554-60. doi: 10.1007/s12471-013-0485-9.

DOI:10.1007/s12471-013-0485-9
PMID:24170231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3833909/
Abstract

BACKGROUND

Recent evidence questions the role of intra-aortic balloon counterpulsation (IABP) in the treatment of acute myocardial infarction (AMI) complicated by cardiogenic shock (CS). An area of increasing interest is the use of IABP for persistent ischaemia (PI). We analysed the use of IABP in patients with AMI complicated by CS or PI.

METHODS

From 2008 to 2010, a total of 4076 patients were admitted to our hospital for primary percutaneous coronary intervention (PCI) for AMI. Out of those, 239 patients received an IABP either because of CS or because of PI. Characteristics and outcome of those patients are investigated.

RESULTS

The mean age of the study population was 64 ± 11 years; 75 % were male patients. Of the patients, 63 % had CS and 37 % had PI. Patients with CS had a 30-day mortality rate of 36 %; 1-year mortality was 41 %. Patients with PI had a 30-day mortality rate of 7 %; 1-year mortality was 11 %.

CONCLUSIONS

Mortality in patients admitted for primary PCI because of AMI complicated by CS is high despite IABP use. Outcome in patients treated with IABP for PI is favourable and mandates further prospective studies.

摘要

背景

近期有证据对主动脉内球囊反搏(IABP)在并发心源性休克(CS)的急性心肌梗死(AMI)治疗中的作用提出质疑。越来越受到关注的一个领域是 IABP 在持续性缺血(PI)中的应用。我们分析了 IABP 在并发 CS 或 PI 的 AMI 患者中的应用。

方法

2008 年至 2010 年,共有 4076 例 AMI 患者接受了我院的直接经皮冠状动脉介入治疗(PCI)。其中,239 例因 CS 或 PI 接受了 IABP 治疗。对这些患者的特征和结局进行了调查。

结果

研究人群的平均年龄为 64±11 岁;75%为男性患者。其中,63%为 CS,37%为 PI。CS 患者的 30 天死亡率为 36%;1 年死亡率为 41%。PI 患者的 30 天死亡率为 7%;1 年死亡率为 11%。

结论

尽管使用了 IABP,因 AMI 并发 CS 而接受直接 PCI 的患者死亡率仍然很高。PI 患者接受 IABP 治疗的预后良好,需要进一步的前瞻性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be04/3833909/02b730ee4e45/12471_2013_485_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be04/3833909/c9a3f29c0272/12471_2013_485_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be04/3833909/02b730ee4e45/12471_2013_485_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be04/3833909/c9a3f29c0272/12471_2013_485_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be04/3833909/02b730ee4e45/12471_2013_485_Fig2_HTML.jpg

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ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation.ST段抬高型急性心肌梗死患者管理的欧洲心脏病学会指南
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主动脉内球囊反搏支持用于伴心原性休克的心肌梗死。
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