Bornman P C, Harries-Jones E P, Tobias R, Van Stiegmann G, Terblanche J
Lancet. 1986 Jan 11;1(8472):69-71. doi: 10.1016/s0140-6736(86)90719-1.
53 patients with obstructive jaundice due to incurable carcinoma of the head of the pancreas were randomly allocated to percutaneous transhepatic placement of a permanent biliary endoprosthesis (PTE) or bypass surgery. After exclusions 25 patients in each group were treated. Technical success was achieved in 21 patients (84%) in the PTE group and 19 (76%) in the surgery group. The incidence of postprocedural complications (PTE 7, surgery 8) and 30-day mortality (PTE 2, surgery 5) were similar. Recurrent jaundice occurred more often in the PTE (8/21) than the surgery group (3/19). Duodenal obstruction developed in 3 patients in the PTE group. Although the initial median postprocedural hospital stay was significantly shorter in the PTE than the surgery group, the difference was no longer significant when readmissions for blocked endoprosthesis and gastric outlet obstruction were taken into account. There was no difference in the median survival time in the two groups (PTE 19 weeks, surgery 15 weeks).
53例因无法治愈的胰头癌导致梗阻性黄疸的患者被随机分配接受经皮经肝胆道永久性内支架置入术（PTE）或旁路手术。排除后，每组25例患者接受治疗。PTE组21例患者（84%）技术成功，手术组19例患者（76%）技术成功。术后并发症发生率（PTE组7例，手术组8例）和30天死亡率（PTE组2例，手术组5例）相似。PTE组（8/21）复发性黄疸的发生率高于手术组（3/19）。PTE组有3例患者出现十二指肠梗阻。虽然PTE组术后最初的中位住院时间明显短于手术组，但将因内支架堵塞和胃出口梗阻再次入院的情况考虑在内后，差异不再显著。两组的中位生存时间无差异（PTE组19周，手术组15周）。
