Universita' degli Studi e I.R.C.C.S. Azienda Ospedaliera Universitaria San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.
J Hypertens. 2014 Jan;32(1):149-53. doi: 10.1097/HJH.0b013e328365b29c.
The Doppler-derived renal resistive index has been used for years in a variety of clinical settings such as the assessment of chronic renal allograft rejection, detection and management of renal artery stenosis, evaluation of progression risk in chronic kidney disease, differential diagnosis in acute and chronic obstructive renal disease, and more recently as a predictor of renal and global outcome in the critically ill patient. More recently, evidence has been accumulating showing that an increased renal resistive index not only reflects changes in intrarenal perfusion but is also related to systemic hemodynamics and the presence of subclinical atherosclerosis, and may thus provide useful prognostic information in patients with primary hypertension. On the basis of these results, the evaluation of renal resistive index has been proposed in the assessment and management of patients with primary hypertension to complement other signs of renal abnormalities.
多普勒衍生的肾阻力指数多年来一直被用于各种临床环境中,如评估慢性肾移植排斥反应、检测和管理肾动脉狭窄、评估慢性肾脏病进展风险、鉴别诊断急性和慢性阻塞性肾病等,最近还被用作危重症患者的肾脏和整体预后的预测指标。最近的证据表明,肾阻力指数的增加不仅反映了肾内灌注的变化,还与全身血液动力学和亚临床动脉粥样硬化的存在有关,因此可能为原发性高血压患者提供有用的预后信息。基于这些结果,肾阻力指数的评估已被提议用于原发性高血压患者的评估和管理,以补充其他肾脏异常的迹象。