Bruni A, Palatini P, Mietto L, Battistella A, Toffano G
Prog Clin Biol Res. 1985;192:507-14.
Unusual phospholipid effects may occur when their distribution in the membrane is altered or when uncontrolled metabolic reactions yield elevated concentrations of their short lived derivatives. Serine phospholipids are normally buried in the internal side of plasma membrane. Upon exposure to the extracellular environment they elicit a response from selected cell populations. The interaction between these phospholipids and neuroactive compounds in rat peritoneal mast cells may indicate that serine phospholipids have a role in the nervous system during development.
当膜中磷脂的分布发生改变,或者不受控制的代谢反应导致其短寿命衍生物浓度升高时,可能会出现异常的磷脂效应。丝氨酸磷脂通常埋藏在质膜内侧。暴露于细胞外环境时,它们会引发特定细胞群体的反应。这些磷脂与大鼠腹膜肥大细胞中神经活性化合物之间的相互作用可能表明,丝氨酸磷脂在发育过程中对神经系统具有一定作用。