溶血磷脂酰丝氨酸依赖性组胺释放的调节
Modulation of lysophosphatidylserine-dependent histamine release.
作者信息
Mietto L, Battistella A, Toffano G, Bruni A
出版信息
Agents Actions. 1984 Apr;14(3-4):376-8. doi: 10.1007/BF01973832.
PMID:6203352
Abstract
Apomorphine (2-30 microM) inhibits lysophosphatidyl-serine-dependent histamine release in rat and mouse peritoneal mast cells. The drug-induced inhibition is influenced by the concentration of lysophosphatidylserine. Log concentration-response curves show a surmountable type of antagonism between the two compounds.
摘要
阿扑吗啡（2 - 30微摩尔）可抑制大鼠和小鼠腹膜肥大细胞中溶血磷脂酰丝氨酸依赖性组胺释放。药物诱导的抑制作用受溶血磷脂酰丝氨酸浓度的影响。对数浓度 - 反应曲线显示这两种化合物之间存在可克服的拮抗类型。
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