Xu Zifeng, Zhang Jianhai, Shen Hao, Zheng Jijian
Department of Anesthesiology, Shanghai First People's Hospital, Shanghai Jiaotong University, 650 Xin Songjiang Road, Shanghai 201620, China.
ScientificWorldJournal. 2013 Sep 19;2013:183493. doi: 10.1155/2013/183493. eCollection 2013.
Whether pulse oximeter perfusion index (PI) may be applied to detect the onset of caudal block in pediatric patients under ketamine intravenous basal anesthesia is investigated. 40 ASA I, 2-8-year-old boys scheduled for elective circumcision surgery were randomized into two groups. Group I: 20 patients were anesthetized by 2 mg·kg(-1) ketamine intravenous injection (IV) followed by caudal block using 1 mL·kg(-1) lidocaine (1%); Group II: 20 patients were anesthetized by 2 mg·kg(-1) ketamine IV only. PI on the toe in Group II decreased by 33 ± 12%, 71 ± 9% and 65 ± 8% at 1 min, 15 min, and 30 min after ketamine injection. The maximum increase in MAP and HR after ketamine IV was 11 ± 6% at 3 min and 10 ± 6% at 2 min. Compared to the PI value before caudal injection of lidocaine, PI in Group I increased by 363 ± 318% and 778 ± 578% at 5 min and 20 min after caudal block, while no significant changes in MAP and HR were found compared to the baseline before caudal block. Thus, PI provides an earlier, more objective, and more sensitive indicator to assess the early onset of caudal block under basal ketamine anesthesia.
研究了脉搏血氧饱和度灌注指数(PI)是否可用于检测氯胺酮静脉基础麻醉下小儿患者骶管阻滞的起效情况。40例计划行择期包皮环切术的2 - 8岁ASA I级男孩被随机分为两组。第一组:20例患者先静脉注射2mg·kg⁻¹氯胺酮,然后使用1mL·kg⁻¹利多卡因(1%)进行骶管阻滞;第二组:20例患者仅静脉注射2mg·kg⁻¹氯胺酮。第二组患者在注射氯胺酮后1分钟、15分钟和30分钟时,脚趾处的PI分别下降了33±12%、71±9%和65±8%。静脉注射氯胺酮后,MAP和HR的最大增幅分别在3分钟时为11±6%,2分钟时为10±6%。与骶管注射利多卡因前的PI值相比,第一组患者在骶管阻滞后5分钟和20分钟时,PI分别增加了363±318%和778±578%,而与骶管阻滞前的基线相比,MAP和HR未发现显著变化。因此,PI为评估氯胺酮基础麻醉下骶管阻滞的早期起效提供了一个更早、更客观、更敏感的指标。