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泰国北部视网膜血管炎的临床特征和病因。

Clinical features and etiology of retinal vasculitis in Northern Thailand.

机构信息

Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

出版信息

Indian J Ophthalmol. 2013 Dec;61(12):739-42. doi: 10.4103/0301-4738.120216.

DOI:10.4103/0301-4738.120216
PMID:24178403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3917393/
Abstract

PURPOSE

To report on the clinical features and etiology of patients with retinal vasculitis (RV).

MATERIALS AND METHODS

We reviewed medical records of 47 patients (75 affected eyes) diagnosed with RV. Clinical presentations, ocular complications, associated systemic diseases, and treatment regimens were registered.

RESULTS

Etiology of RV included infectious causes in 10/47, (21%) while an association with systemic and/or ocular non-infectious disorders was noted in 22/47 (47%). Eales' disease and Behcet's disease represented the most common clinical entities in non-infectious group while tuberculosis-associated RV was diagnosed in 6/10 (60%) among those with infectious disorders. RV was bilateral in 28/47 (60%) patients. Retinal veins were most commonly affected (72%, 34/47). Involvement of arteries was present in 12/47 (25%) and was associated with viral infections and Behcet's disease. Ocular complications developed in 60/75 (80%) eyes. The most common complications were elevated intraocular pressure and/or glaucoma (33/75, 44%). Retinal detachment, vitreous hemorrhage, and cystoid macular edema developed in similar percentages (15%).

CONCLUSIONS

RV in Thailand manifested mostly in male patients, was typically bilateral and involved mostly veins. Involvement of arteries was observed in patients with viral infections and Behcet's disease. Tuberculosis was the most common infectious cause.

摘要

目的

报告视网膜血管炎(RV)患者的临床特征和病因。

材料与方法

我们回顾了 47 例(75 只患眼)诊断为 RV 的患者的病历。记录了临床表现、眼部并发症、相关系统性疾病和治疗方案。

结果

RV 的病因包括感染性病因 10/47(21%),而与系统性和/或非感染性眼部疾病相关的病因 22/47(47%)。非感染性病因中以 Eales 病和 Behcet 病最为常见,而感染性病因中则诊断出结核相关 RV 6/10(60%)。47 例患者中 28/47(60%)为双眼受累。最常受累的是视网膜静脉(72%,34/47)。动脉受累见于 12/47(25%),与病毒感染和 Behcet 病相关。60/75(80%)只眼中出现眼部并发症。最常见的并发症是眼内压升高和/或青光眼(33/75,44%)。视网膜脱离、玻璃体积血和黄斑囊样水肿的发生率相似(15%)。

结论

泰国的 RV 主要发生在男性患者中,通常为双眼受累,且主要累及静脉。动脉受累见于病毒感染和 Behcet 病患者。结核病是最常见的感染性病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb97/3917393/8e537bfe4909/IJO-61-739-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb97/3917393/8e537bfe4909/IJO-61-739-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb97/3917393/8e537bfe4909/IJO-61-739-g003.jpg

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Indirect supportive evidence for diagnosis of tuberculosis-related uveitis: from the tuberculin skin test to the new interferon gamma release assays.诊断结核相关性葡萄膜炎的间接支持证据:从结核菌素皮肤试验到新型干扰素γ释放试验。
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Ocul Immunol Inflamm. 2012 Jun;20(3):153-7. doi: 10.3109/09273948.2012.658134. Epub 2012 Apr 9.
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Patients with retinal vasculitis rarely suffer from systemic vasculitis.视网膜血管炎患者很少患有全身血管炎。
Semin Arthritis Rheum. 2012 Jun;41(6):859-65. doi: 10.1016/j.semarthrit.2011.10.006. Epub 2011 Dec 15.
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