Tandon B N, Gandhi B M, Joshi Y K, Irshad M, Gupta H
Bull World Health Organ. 1985;63(5):931-4.
Serological studies of hepatitis viruses A and B were carried out on 362 patients with acute viral hepatitis, 130 with fulminant hepatitis, and 56 with subacute hepatitis, and on samples of serum from 230 subjects during epidemics of viral hepatitis. A diagnosis of non-A, non-B viral hepatitis was made when serological tests showed that anti-HAV IgM and anti-HBc IgM were absent. Hepatitis virus non-A, non-B was the causative agent responsible for 58% of cases with acute viral hepatitis, 58% with fulminant hepatitis, 87% with subacute hepatitis, and 66% with epidemic hepatitis. A considerable proportion of patients (6-32%) were infected with both hepatitis virus non-A, non-B and hepatitis virus B. Viral hepatitis non-A, non-B is probably transmitted by infection of drinking-water and is the principal cause of hepatitis in India.
对362例急性病毒性肝炎患者、130例暴发性肝炎患者和56例亚急性肝炎患者,以及230名病毒性肝炎流行期间受试者的血清样本进行了甲型和乙型肝炎病毒的血清学研究。当血清学检测显示抗甲型肝炎病毒IgM和抗乙型肝炎核心抗体IgM均不存在时,诊断为非甲非乙型病毒性肝炎。非甲非乙型肝炎病毒是58%的急性病毒性肝炎病例、58%的暴发性肝炎病例、87%的亚急性肝炎病例和66%的流行性肝炎病例的致病因子。相当一部分患者(6%-32%)同时感染了非甲非乙型肝炎病毒和乙型肝炎病毒。非甲非乙型病毒性肝炎可能通过饮用水感染传播,是印度肝炎的主要病因。