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尼古丁:昨天、今天和明天——全球综述。

Nicotine yesterday, today, and tomorrow: a global review.

机构信息

Cancer Council Victoria, Carlton, Victoria, Australia.

出版信息

Nicotine Tob Res. 2014 Feb;16(2):128-36. doi: 10.1093/ntr/ntt171. Epub 2013 Nov 5.

DOI:10.1093/ntr/ntt171
PMID:24191982
Abstract

This intentionally selective global review reflects the views and frustrations of a public health physician with 45 years of frontline experience in tobacco control. In particular, it focuses on the nexus between research and policy and the long periods between relevant discoveries and application as policy. Consideration is given to the relative neglect of the possibility of reducing the carcinogenicity and toxicity of the cigarette on the grounds that it is the preferred source of nicotine for the global majority of nicotine users. Although the outcome of such change is unquantifiable, there is much in cigarette smoke that can be changed to make it less carcinogenic and less toxic. It is difficult to think of excuses for accepting the status quo.

摘要

这是一次有选择性的全球性回顾,反映了一位具有 45 年前线烟草控制经验的公共卫生医生的观点和挫折感。特别是,它侧重于研究与政策之间的关系,以及相关发现与政策应用之间的长时间滞后。人们考虑到,由于香烟是全球大多数尼古丁使用者首选的尼古丁来源,因此相对忽视了降低香烟致癌性和毒性的可能性。尽管这种改变的结果无法量化,但香烟烟雾中有很多可以改变的地方,可以使其致癌性和毒性降低。很难为接受现状找借口。

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