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[糖尿病患者纤维蛋白原的行为与眼底客观血管测量结果的比较]

[Behavior of fibrinogen in diabetic patients in comparison with objective vascular measurements in the ocular fundus].

作者信息

Syrbe G, Oswald B, Jorke D, Jütte A

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1985;112(6):853-8.

PMID:2419213
Abstract

Objective measurements of vessels were performed in vivo in 10 patients affected with diabetes mellitus, the fibrinogen concentrations in the venous blood being determined simultaneously. Whereas the ensured correlations with fibrinogen concentration could be recognized from the diameter of arteries and veins and from the flow velocity, a linear correlation could be found to exist between the fibrinogen level and the volume flowing through a retinal artery. These findings prove that the very existence of a hyperfibrinogen anemia does not justify the assumption of the blood volume flow being decreased. In patients with diabetes mellitus the enhanced volume flowing through retinal arteries is rather connected with an increased fibrinogen level.

摘要

对10名糖尿病患者进行了体内血管的客观测量,同时测定静脉血中的纤维蛋白原浓度。虽然从动脉和静脉的直径以及血流速度可以看出与纤维蛋白原浓度有确定的相关性,但发现纤维蛋白原水平与通过视网膜动脉的血流量之间存在线性关系。这些发现证明,高纤维蛋白原血症的存在本身并不能证明血容量减少的假设是合理的。在糖尿病患者中,通过视网膜动脉的血流量增加与纤维蛋白原水平升高有关。

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Folia Haematol Int Mag Klin Morphol Blutforsch. 1985;112(6):853-8.
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