Lawson Health Research Institute, Aging Rehabilitation and Geriatric Care Research Centre, 801 Commissioners Rd E, Ste B 3002, London, Ontario N6C 5J1, Canada.
BMC Public Health. 2013 Nov 7;13:1051. doi: 10.1186/1471-2458-13-1051.
Metabolic syndrome is a cluster of cardiovascular risk factors that greatly increase the risk of developing cardiovascular disease and type 2 diabetes. Regular exercise improves the risk profile, but most people do not successfully change their exercise habits to beneficially reduce risk. Tailored exercise prescribed by a family physician has shown promise as a means to increase fitness and reduce cardiometabolic risk, but optimal implementation practices remain unknown. Mobile health technologies have proved to be a beneficial tool to achieve blood pressure and blood glucose control in patients with diabetes. These technologies may address the limited access to health interventions in rural and remote regions. However, the potential as a tool to support exercise-based prevention activities is not well understood. This study was undertaken to investigate the effects of a tailored exercise prescription alone or supported by mobile health technologies to improve metabolic syndrome and related cardiometabolic risk factors in rural community-dwelling adults at risk for cardiovascular disease and type 2 diabetes.
METHODS/DESIGN: Adults (n = 149) with at least two metabolic syndrome risk factors were recruited from rural communities and randomized to either: 1) an intervention group receiving an exercise prescription and devices for monitoring of risk factors with a smartphone data portal equipped with a mobile health application; or 2) an active control group receiving only an exercise prescription. All participants reported to the research centre at baseline, and at 12-, 24- and 52-week follow-up visits for measurement of anthropometrics and blood pressure and for a blood draw to test blood-borne markers of cardiometabolic health. Vascular and autonomic function were examined. Fitness was assessed and exercise prescribed according to the Step Test and Exercise Prescription protocol.
This study tested the effects of a prescriptive exercise intervention alone, versus one supported by mobile health technology on cardiometabolic risk factors. The intervention was designed to be translated into clinical or community-based programming. Results will contribute to the current literature by investigating the utility of mobile health technology support for exercise prescription interventions to improve cardiometabolic risk status and maintain improvements over time; particularly in rural communities.
NCT01944124.
代谢综合征是一组心血管危险因素，会大大增加患心血管疾病和 2 型糖尿病的风险。经常运动可以改善风险状况，但大多数人无法成功改变运动习惯，从而降低风险。家庭医生开出的量身定制的运动方案已被证明是一种提高健康水平和降低心血管代谢风险的有效方法，但最佳实施方法仍不清楚。移动健康技术已被证明是控制糖尿病患者血压和血糖的有益工具。这些技术可以解决农村和偏远地区获得健康干预措施有限的问题。然而，作为支持基于运动的预防活动的工具的潜力尚未得到充分理解。本研究旨在探讨单独使用或结合移动健康技术支持的个性化运动方案对改善农村社区居住的心血管疾病和 2 型糖尿病高危人群的代谢综合征和相关心血管代谢危险因素的效果。
方法/设计：从农村社区招募至少有两种代谢综合征危险因素的成年人（n=149），并将他们随机分为以下两组：1）干预组，接受运动处方和用于监测危险因素的设备，包括配备移动健康应用程序的智能手机数据门户；或 2）主动对照组，仅接受运动处方。所有参与者在基线时、12 周、24 周和 52 周随访时到研究中心报到，进行身体测量、血压测量和血液采集以检测心血管代谢健康的血液标志物。还检查了血管和自主神经功能。根据台阶测试和运动处方方案评估了健康状况并开出运动处方。
本研究测试了单独的规范性运动干预与通过移动健康技术支持的运动干预对心血管代谢风险因素的影响。该干预措施旨在转化为临床或基于社区的方案。研究结果将通过调查移动健康技术支持对改善心血管代谢风险状况和随着时间的推移保持改善的运动处方干预的实用性，为当前文献做出贡献，特别是在农村社区。
NCT01944124。
