Fjellner B, Arnetz B B
Acta Derm Venereol. 1985;65(6):504-8.
Experimentally-induced mental stress activates the psychoneuroendocrine systems. The cutaneous (itch and flare) responses of human skin to intradermal injection of histamine remain despite this unaltered. Major interindividual differences, however, exist in both neurophysiological reactions and cutaneous reactivity. The individual skin responses are interrelated to the urinary adrenaline response pattern. Psychosomatic status and psychosocial factors were in this study observed to be good predictors of skin responsiveness assessed by a multivariate model. We suggest that future studies on stress and pruritus should take these aspects into consideration. Knowledge of individual characteristics and coping strategies might help us understand why some patients suffer form itching in response to stress while others do not.
实验诱导的精神压力会激活心理神经内分泌系统。尽管如此，人类皮肤对皮内注射组胺的皮肤（瘙痒和潮红）反应仍未改变。然而，神经生理反应和皮肤反应性方面都存在较大的个体差异。个体的皮肤反应与尿肾上腺素反应模式相关。在本研究中，通过多变量模型观察到身心状态和社会心理因素是皮肤反应性的良好预测指标。我们建议未来关于压力和瘙痒的研究应考虑这些方面。了解个体特征和应对策略可能有助于我们理解为什么有些患者在压力下会出现瘙痒而有些则不会。
