• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人类和豚鼠子宫的肽能神经支配

Peptidergic innervation of the human and guinea pig uterus.

作者信息

Heinrich D, Reinecke M, Forssmann W G

出版信息

Arch Gynecol. 1986;237(4):213-9. doi: 10.1007/BF02133783.

DOI:10.1007/BF02133783
PMID:2421649
Abstract

The peptidergic innervation of the human and guinea pig uterus was studied using immunohistochemical methods. Antibodies against several peptides were applied for the PAP-technique to stain peptidergic nerves specifically. These are located in the adventitia of large uterine vessels in the myometrium and smaller vessels of the myometrium and endometrium. A differential distribution of the individual peptides was observed for VIP-IR (vasoactive intestinal polypeptide immunoreactivity), NPY-IR (neuropeptide Y), SP-IR (substance P), SOM-IR (somatostatin) and NT-IR (neurotensin) nerve fibers. Specific functional implications for these neuropeptides can be derived from their histochemical location.

摘要

采用免疫组织化学方法研究了人和豚鼠子宫的肽能神经支配。将针对几种肽的抗体应用于过氧化物酶抗过氧化物酶技术(PAP技术),以特异性地染色肽能神经。这些神经位于子宫肌层中大子宫血管的外膜以及子宫肌层和子宫内膜的较小血管中。观察到血管活性肠肽免疫反应性(VIP-IR)、神经肽Y(NPY-IR)、P物质免疫反应性(SP-IR)、生长抑素免疫反应性(SOM-IR)和神经降压素免疫反应性(NT-IR)神经纤维中各肽的分布存在差异。这些神经肽的特定功能意义可从其组织化学定位推导得出。

相似文献

1
Peptidergic innervation of the human and guinea pig uterus.人类和豚鼠子宫的肽能神经支配
Arch Gynecol. 1986;237(4):213-9. doi: 10.1007/BF02133783.
2
[Peptidergic (NPY, NT, VIP, SP, CGRP) innervation of the functional systems of the uterus and fallopian tube in the human].[人子宫和输卵管功能系统的肽能(神经肽Y、神经降压素、血管活性肠肽、P物质、降钙素基因相关肽)神经支配]
Arch Gynecol Obstet. 1989;245(1-4):399-401. doi: 10.1007/BF02417342.
3
Neuropeptide (neuropeptide Y, neurotensin, vasoactive intestinal polypeptide, substance P, calcitonin gene-related peptide, somatostatin) immunohistochemistry and ultrastructure of renal nerves.肾神经的神经肽(神经肽Y、神经降压素、血管活性肠多肽、P物质、降钙素基因相关肽、生长抑素)免疫组织化学及超微结构
Histochemistry. 1988;89(1):1-9. doi: 10.1007/BF00496578.
4
Peptidergic innervation of the mammalian sinus nodes: vasoactive intestinal polypeptide, neurotensin, substance P.哺乳动物窦房结的肽能神经支配:血管活性肠肽、神经降压素、P物质。
Neurosci Lett. 1981 Nov 4;26(3):283-8. doi: 10.1016/0304-3940(81)90146-4.
5
Ultrastructural localisation of substance P, vasoactive intestinal polypeptide, somatostatin and neuropeptide Y immunoreactivity in perivascular nerve plexuses of the gut.P物质、血管活性肠肽、生长抑素和神经肽Y免疫反应性在肠道血管周围神经丛中的超微结构定位
Blood Vessels. 1986;23(3):125-36. doi: 10.1159/000158629.
6
Co-existence and origin of peptidergic and adrenergic nerves in the guinea pig uterus. Retrograde tracing and immunocytochemistry, effects of chemical sympathectomy, capsaicin treatment and pregnancy.豚鼠子宫中肽能神经与肾上腺素能神经的共存及起源。逆行追踪与免疫细胞化学、化学交感神经切除术、辣椒素处理及妊娠的影响。
Cell Tissue Res. 1988;254(3):517-30. doi: 10.1007/BF00226501.
7
The peptidergic innervation of the guinea pig uterine artery in pregnancy.豚鼠妊娠子宫动脉的肽能神经支配
Basic Appl Histochem. 1988;32(1):153-9.
8
Immunohistochemical study of the distribution of adrenergic and peptidergic innervation in the equine uterus and the cervix.马子宫和子宫颈中肾上腺素能和肽能神经支配分布的免疫组织化学研究。
Reproduction. 2001 Aug;122(2):275-82. doi: 10.1530/rep.0.1220275.
9
Tissue distribution and innervation pattern of peptide immunoreactivities in the rat pancreas.大鼠胰腺中肽免疫反应性的组织分布和神经支配模式
Peptides. 1992 Jan-Feb;13(1):91-8. doi: 10.1016/0196-9781(92)90145-s.
10
Multiple neuropeptides in nerves supplying mammalian lymph nodes: messenger candidates for sensory and autonomic neuroimmunomodulation?供应哺乳动物淋巴结的神经中的多种神经肽:感觉和自主神经免疫调节的信使候选物?
Neurosci Lett. 1988 Jul 19;90(1-2):39-44. doi: 10.1016/0304-3940(88)90783-5.

引用本文的文献

1
Distribution of Nerve Fibers in Abdominal Wall Endometriosis and Their Clinical Significance.腹壁子宫内膜异位症中神经纤维的分布及其临床意义
J Pain Res. 2024 Apr 24;17:1563-1570. doi: 10.2147/JPR.S453148. eCollection 2024.
2
Tachykinins and tachykinin receptors in human uterus.人类子宫中的速激肽和速激肽受体
Br J Pharmacol. 2003 Jun;139(3):523-32. doi: 10.1038/sj.bjp.0705279.
3
Functional characterization of tachykinin NK1 receptors in the mouse uterus.小鼠子宫中速激肽NK1受体的功能特性

本文引用的文献

1
The innervation of the cervix and cornu uteri in the rabbit.家兔子宫颈和子宫角的神经支配
J Physiol. 1952 Jul;117(3):317-28. doi: 10.1113/jphysiol.1952.sp004751.
2
The differential distribution of vasoactive intestinal polypeptide in the normal human female genital tract.血管活性肠肽在正常女性生殖道中的差异分布。
Histochemistry. 1980;67(2):169-77. doi: 10.1007/BF00493234.
3
Origin and distribution of VIP (vasoactive intestinal polypeptide)-nerves in the genito-urinary tract.泌尿生殖道中血管活性肠肽(VIP)神经的起源与分布。
Br J Pharmacol. 2002 Dec;137(8):1247-54. doi: 10.1038/sj.bjp.0704996.
4
Maternal decidua and fetal membranes contain immunoreactive neuropeptide Y.母体蜕膜和胎膜含有免疫反应性神经肽Y。
J Endocrinol Invest. 1993 Mar;16(3):201-5. doi: 10.1007/BF03344947.
5
Immunohistochemical and biological evidence for a neuromodulator function of neuropeptide Y in the human oviduct.神经肽Y在人输卵管中神经调节功能的免疫组化及生物学证据。
Arch Gynecol Obstet. 1987;241(2):127-32. doi: 10.1007/BF00931233.
6
Organization of the guinea-pig uterine innervation. Distribution of immunoreactivities for different neuronal markers. Effects of chemical- and pregnancy-induced sympathectomy.豚鼠子宫神经支配的组织学。不同神经元标志物免疫反应性的分布。化学性和妊娠诱导的交感神经切除术的影响。
Histochem J. 1988 May;20(5):290-300. doi: 10.1007/BF01745608.
7
Immunohistochemical localization of calcitonin gene-related peptide and bombesin/gastrin-releasing peptide in nerve fibers of the rat, guinea pig and pig female genital organs.大鼠、豚鼠和猪雌性生殖器官神经纤维中降钙素基因相关肽和蛙皮素/胃泌素释放肽的免疫组织化学定位
Histochemistry. 1989;92(3):211-8. doi: 10.1007/BF00500920.
8
Co-existence and origin of peptidergic and adrenergic nerves in the guinea pig uterus. Retrograde tracing and immunocytochemistry, effects of chemical sympathectomy, capsaicin treatment and pregnancy.豚鼠子宫中肽能神经与肾上腺素能神经的共存及起源。逆行追踪与免疫细胞化学、化学交感神经切除术、辣椒素处理及妊娠的影响。
Cell Tissue Res. 1988;254(3):517-30. doi: 10.1007/BF00226501.
9
An immunohistochemical study of the catecholamine synthesizing enzymes and neuropeptides in the female guinea-pig uterus and vagina.雌性豚鼠子宫和阴道中儿茶酚胺合成酶及神经肽的免疫组织化学研究
Histochem J. 1992 Jun;24(6):361-7. doi: 10.1007/BF01046168.
Cell Tissue Res. 1980;205(3):337-47. doi: 10.1007/BF00232276.
4
Effect of vasoactive intestinal polypeptide (VIP) upon myometrial blood flow in non-pregnant rabbit.血管活性肠肽(VIP)对未孕兔子宫肌层血流的影响。
Acta Physiol Scand. 1981 Jun;112(2):195-201. doi: 10.1111/j.1748-1716.1981.tb06804.x.
5
Enkephalin-immunoreactive nerve fibers in the feline genito-urinary tract.猫泌尿生殖道中脑啡肽免疫反应性神经纤维。
Histochemistry. 1981;72(3):351-5. doi: 10.1007/BF00501777.
6
On the VIP-ergic innervation of the uterotubal junction.关于子宫输卵管连接处的血管活性肠肽能神经支配。
Acta Physiol Scand. 1981 Feb;111(2):213-5. doi: 10.1111/j.1748-1716.1981.tb06727.x.
7
The endocrine regulation of uterine blood flow in the nonpregnant uterus: a review.非妊娠子宫中子宫血流的内分泌调节:综述
Am J Obstet Gynecol. 1981 May 15;140(2):151-6. doi: 10.1016/0002-9378(81)90102-2.
8
Effects of VIP in the female genital tract.血管活性肠肽在女性生殖道中的作用。
Endocrinol Jpn. 1980 Dec;27 Suppl 1:71-8. doi: 10.1507/endocrj1954.27.supplement_71.
9
Endometrial cholinergic secretory responses during estrous cycle, pregnancy and after estrogen and/or progesterone treatment of the guinea-pig.豚鼠发情周期、孕期以及雌激素和/或孕激素处理后子宫内膜的胆碱能分泌反应。
Acta Physiol Scand. 1980 Nov;110(3):233-40. doi: 10.1111/j.1748-1716.1980.tb06659.x.
10
Cholinergic nerves in mouse uterus.小鼠子宫中的胆碱能神经。
J Neural Transm. 1982;55(2):139-48. doi: 10.1007/BF01243756.