Heinrich D, Reinecke M, Forssmann W G
Arch Gynecol. 1986;237(4):213-9. doi: 10.1007/BF02133783.
The peptidergic innervation of the human and guinea pig uterus was studied using immunohistochemical methods. Antibodies against several peptides were applied for the PAP-technique to stain peptidergic nerves specifically. These are located in the adventitia of large uterine vessels in the myometrium and smaller vessels of the myometrium and endometrium. A differential distribution of the individual peptides was observed for VIP-IR (vasoactive intestinal polypeptide immunoreactivity), NPY-IR (neuropeptide Y), SP-IR (substance P), SOM-IR (somatostatin) and NT-IR (neurotensin) nerve fibers. Specific functional implications for these neuropeptides can be derived from their histochemical location.
采用免疫组织化学方法研究了人和豚鼠子宫的肽能神经支配。将针对几种肽的抗体应用于过氧化物酶抗过氧化物酶技术(PAP技术),以特异性地染色肽能神经。这些神经位于子宫肌层中大子宫血管的外膜以及子宫肌层和子宫内膜的较小血管中。观察到血管活性肠肽免疫反应性(VIP-IR)、神经肽Y(NPY-IR)、P物质免疫反应性(SP-IR)、生长抑素免疫反应性(SOM-IR)和神经降压素免疫反应性(NT-IR)神经纤维中各肽的分布存在差异。这些神经肽的特定功能意义可从其组织化学定位推导得出。