IEEE Trans Med Imaging. 2014 Feb;33(2):535-45. doi: 10.1109/TMI.2013.2289930. Epub 2013 Nov 7.
Optoacoustic (photoacoustic) imaging uniquely visualizes optical contrast in high resolution and comes with very attractive characteristics for clinical imaging applications. In this paper, we showcase the performance of a scanner based on a 24 MHz center-frequency 128 element array, developed for applications in dermatology. We perform system characterization to examine the imaging performance achieved. We then showcase its imaging ability on healthy tissue and cancer. Finally, we image burns and human lesions in vivo and gain insights on the benefits and challenges of this approach as it is considered for diagnostic and treatment follow-up applications in dermatology and beyond.
光声(超声)成像是一种独特的高分辨率光学对比度成像技术,具有非常吸引人的临床成像应用特性。在本文中,我们展示了一种基于 24MHz 中心频率 128 元阵列的扫描仪的性能,该扫描仪专为皮肤科应用而开发。我们进行了系统特性分析,以检查所达到的成像性能。然后,我们展示了它在健康组织和癌症上的成像能力。最后,我们对体内烧伤和人体病变进行了成像,并深入了解了这种方法在皮肤科及其他领域的诊断和治疗随访应用中的优势和挑战。