Jenkins D J, Rickard M D
Aust Vet J. 1986 Feb;63(2):40-2. doi: 10.1111/j.1751-0813.1986.tb02918.x.
Groups of dogs raised free of helminths were monospecifically infected with the common nematodes Toxocara canis, Ancylostoma caninum and Trichuris vulpis. Serums from these dogs, and a group of dogs of unknown history but infected with Dirofilaria immitis and Dipylidium caninum, had levels of antibody to their homologous nematode antigens readily detectable by ELISA. No cross-reactions were apparent when these serums were tested by ELISA using oncosphere antigens of Taenia hydatigena, T. pisiformis and T. ovis, scolex excretory/secretory antigens of T. hydatigena, T. pisiformis and Echinococcus granulosus or protoscolex antigen of E. granulosus.
在无蠕虫环境下饲养的几组犬分别被常见的线虫——犬弓首蛔虫、犬钩口线虫和狐毛首线虫单种感染。这些犬的血清,以及一组病史不明但感染了犬恶丝虫和犬复孔绦虫的犬的血清,其针对同源线虫抗原的抗体水平通过酶联免疫吸附测定法(ELISA)很容易检测到。当使用泡状带绦虫、豆状带绦虫和绵羊带绦虫的六钩蚴抗原、泡状带绦虫、豆状带绦虫和细粒棘球绦虫的头节排泄/分泌抗原或细粒棘球绦虫的原头节抗原通过ELISA对这些血清进行检测时,未出现明显的交叉反应。