Department of Chemistry, Michigan State University, 48824, East Lansing, MI, USA.
J Am Soc Mass Spectrom. 1993 Sep;4(9):751-4. doi: 10.1016/1044-0305(93)80055-4.
High efficiency photo-induced dissociation (PID) has been demonstrated in a tandem time-of-flight mass spectrometer. This instrument focuses isomass ion packets to temporal and spatial dimensions similar to those of the focused laser pulses from a high power excimer laser. This high density overlap of photons and ions yields highly efficient fragmentation and also provides high resolution selection of specific precursor ion mass-to-charge ratio values. Using 193 nm photon excitation of the molecular ion of bromobenzene (m/z = 1561, fragmentation, collection, and PID efficiencies af 79%, 132%, and 104%, respectively, were obtained. Characteristic fragmentations of toluene, nitrobenzene, acetophenone, triethylamine, N,N-diethylformamide, N-methylacetamide, and cyclohexene have also been demonstrated.
在串联飞行时间质谱仪中已经证明了高效光致离解（PID）。该仪器将等质荷比离子包聚焦到类似于高强度准分子激光聚焦激光脉冲的时间和空间维度。这种光子和离子的高密度重叠产生了高效的碎片化，并且还提供了特定前体离子质荷比值的高分辨率选择。使用 193nm 光子激发溴苯的分子离子（m/z=1561），分别获得了 79%、132%和 104%的碎片化、收集和 PID 效率。还证明了甲苯、硝基苯、苯乙酮、三乙胺、N,N-二甲基甲酰胺、N-甲基乙酰胺和环己烯的特征碎片化。
