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玻璃体内注射贝伐单抗成功治疗黑素细胞瘤相关性脉络膜新生血管膜

Successful treatment of melanocytoma associated choroidal neovascular membrane with intravitreal bevacizumab.

作者信息

Al-Halafi Ali M

机构信息

Department of Surgery, Ophthalmology Division, Security Forces Hospital, Riyadh, Saudi Arabia.

出版信息

Saudi J Ophthalmol. 2013 Apr;27(2):117-9. doi: 10.1016/j.sjopt.2012.12.002. Epub 2013 Jan 5.

Abstract

Melanocytoma of the optic disc is a benign melanocytic tumour that rarely causes visual impairment. We report a rare case of choroidal neovascularization (CNV) in association with optic disc melanocytoma and its response to intravitreal injection of the anti-vascular endothelial growth factor (VEGF), bevacizumab. The choroidal neovascular membrane regressed following a single intravitreal bevacizumab injection with formation of a scar. CNV associated with optic disc melanocytoma is rare. Intravitreal anti-VEGF treatment may be an effective treatment for CNV associated with optic disc melanocytoma.

摘要

视盘黑色素细胞瘤是一种良性黑素细胞肿瘤,很少引起视力损害。我们报告一例罕见的脉络膜新生血管形成(CNV)合并视盘黑色素细胞瘤病例,以及其对玻璃体内注射抗血管内皮生长因子(VEGF)药物贝伐单抗的反应。单次玻璃体内注射贝伐单抗后,脉络膜新生血管膜消退并形成瘢痕。视盘黑色素细胞瘤相关的CNV很罕见。玻璃体内抗VEGF治疗可能是视盘黑色素细胞瘤相关CNV的有效治疗方法。

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