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急性心肌梗死并发休克:基于初始心电图的预后分析。

Acute myocardial infarction complicated by shock: outcome analysis based on initial electrocardiogram.

机构信息

1st Department of Internal Medicine - Cardioangiology, University Hospital Hradec Kralove , Czech Republic.

出版信息

Scand Cardiovasc J. 2014 Feb;48(1):13-9. doi: 10.3109/14017431.2013.865074. Epub 2013 Dec 13.

Abstract

OBJECTIVES

To assess the relation between initial ECG findings, presence of risk factors, coronary angiography findings, and clinical outcomes in patients with acute myocardial infarction complicated by cardiogenic shock (CS).

DESIGN

Data from a total of 5572 acute myocardial infarction patients admitted to the four tertiary hospitals during a period of 3 years were analyzed. CS on admission was present in 358 patients (6.4%). They were divided into four groups based on the admission ECG: ST-segment elevation (STEMI), ST-segment depression (STDMI), bundle branch block (BBBMI), and other ECG acute myocardial infarction.

RESULTS

CS developed most frequently among BBBMI patients (in 12.1% of all BBBMIs, p < 0.001 vs. STEMI), followed by STEMI (6.7%), STDMI (4.4%), and other ECG acute myocardial infarction (2.3%). The risk of CS development was similar in patients with left bundle branch block (LBBB) (13.3%) and right bundle branch block (RBBB) (11.2%). The one-year mortality was highest among RBBBMI patients (66.7%, p < 0.001), followed by LBBBMI (48.6%), other ECG (47.1%), STEMI (41.7%), and STDMI patients (38.1%).

CONCLUSIONS

RBBB on admission ECG is associated with the highest risk of CS development, frequent left main coronary artery affection, and unsuccessful revascularization. It is also an independent predictor of one-year mortality.

摘要

目的

评估急性心肌梗死并发心源性休克(CS)患者的初始心电图表现、危险因素、冠状动脉造影结果与临床结局之间的关系。

设计

分析了 3 年内 4 家三级医院共 5572 例急性心肌梗死患者的数据。入院时 CS 存在于 358 例患者(6.4%)中。他们根据入院心电图分为 4 组:ST 段抬高(STEMI)、ST 段压低(STDMI)、束支传导阻滞(BBBMI)和其他心电图急性心肌梗死。

结果

CS 最常发生在 BBBMI 患者中(所有 BBBMI 中占 12.1%,p < 0.001 与 STEMI 相比),其次是 STEMI(6.7%)、STDMI(4.4%)和其他心电图急性心肌梗死(2.3%)。左束支传导阻滞(LBBB)(13.3%)和右束支传导阻滞(RBBB)(11.2%)患者发生 CS 的风险相似。RBBBMI 患者的一年死亡率最高(66.7%,p < 0.001),其次是 LBBBMI(48.6%)、其他心电图(47.1%)、STEMI(41.7%)和 STDMI 患者(38.1%)。

结论

入院时心电图的 RBBB 与 CS 发展的风险最高、左主干冠状动脉受累频繁以及血运重建不成功相关。它也是一年死亡率的独立预测因素。

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