Mt. Hope Family Center, University of Rochester.
Dev Psychopathol. 2013 Nov;25(4 Pt 1):1065-78. doi: 10.1017/S0954579413000370.
A randomized clinical trial was conducted to evaluate the efficacy of interpersonal psychotherapy (IPT) for ethnically and racially diverse, economically disadvantaged women with major depressive disorder. Non-treatment-seeking urban women (N = 128; M age = 25.40, SD = 4.98) with infants were recruited from the community. Participants were at or below the poverty level: 59.4% were Black and 21.1% were Hispanic. Women were screened for depressive symptoms using the Center for Epidemiologic Studies Depression Scale; the Diagnostic Interview Schedule was used to confirm major depressive disorder diagnosis. Participants were randomized to individual IPT or enhanced community standard. Depressive symptoms were assessed before, after, and 8 months posttreatment with the Beck Depression Inventory-II and the Revised Hamilton Rating Scale for Depression. The Social Support Behaviors Scale, the Social Adjustment Scale-Self-Report, and the Perceived Stress Scale were administered to examine mediators of outcome at follow-up. Treatment effects were evaluated with a growth mixture model for randomized trials using complier-average causal effect estimation. Depressive symptoms trajectories from baseline through postintervention to follow-up showed significant decreases among the IPT group compared to the enhanced community standard group. Changes on the Perceived Stress Scale and the Social Support Behaviors Scale mediated sustained treatment outcome.
一项随机临床试验评估了人际心理治疗（IPT）对于具有不同种族和民族、经济困难的、患有重度抑郁症的女性的疗效。该研究招募了来自社区的、未接受治疗的城市女性（N=128；M 年龄=25.40，SD=4.98），她们都有婴儿。参与者的收入都在贫困线以下：59.4%是黑人，21.1%是西班牙裔。使用流行病学研究中心抑郁量表（CES-D）对女性进行抑郁症状筛查；使用诊断性访谈量表（DIS）来确诊重度抑郁症。参与者被随机分配到个体 IPT 治疗组或增强社区标准治疗组。使用贝克抑郁自评量表第二版（BDI-II）和汉密尔顿抑郁评定量表修订版（HRSD）在治疗前、治疗后和治疗后 8 个月评估抑郁症状。社会支持行为量表、社会适应量表自我报告版（SAS-SR）和感知压力量表（PSS）用于在随访时评估结果的中介因素。使用随机试验的增长混合模型和遵从平均因果效应估计来评估治疗效果。与增强社区标准组相比，IPT 组从基线到干预后再到随访的抑郁症状轨迹显著下降。感知压力量表和社会支持行为量表的变化中介了持续的治疗效果。
