Binh Tran Thanh, Suzuki Rumiko, Shiota Seiji, Kwon Dong Hyeon, Yamaoka Yoshio
Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu, Japan.
Genome Announc. 2013 Nov 14;1(6):e00912-13. doi: 10.1128/genomeA.00912-13.
We report the complete genome sequences of two Helicobacter pylori clarithromycin-resistant strains. Clarithromycin (CLR)-resistant strains were obtained under the exposure of H. pylori strain 26695 on agar plates with low clarithromycin concentrations. The genome data provide insights into the genomic changes of H. pylori under selection by clarithromycin in vitro.
我们报告了两株耐克拉霉素的幽门螺杆菌的全基因组序列。在低浓度克拉霉素的琼脂平板上培养幽门螺杆菌菌株26695,从而获得了耐克拉霉素(CLR)菌株。这些基因组数据为体外克拉霉素选择条件下幽门螺杆菌的基因组变化提供了见解。