Shiota Seiji, Yamaoka Yoshio
F1000 Med Rep. 2010 Mar 15;2:20. doi: 10.3410/M2-20.
Meta-analysis has shown that successful Helicobacter pylori eradication therapy improved atrophic gastritis and intestinal metaplasia. Moreover, successful eradication therapy against atrophic gastritis has led to the suppression of the incidence of metachronous gastric cancer. Thus, the Japanese Society for Helicobacter Research concluded that all 'H. pylori-infected persons' should be considered for eradication therapy, irrespective of any background diseases. Successful eradication can prevent transmission of this bacterium, and recent publications show that curing H. pylori infection seems to reduce the risk of gastric cancer.
荟萃分析表明，成功的幽门螺杆菌根除治疗可改善萎缩性胃炎和肠化生。此外，针对萎缩性胃炎的成功根除治疗已导致异时性胃癌发病率的降低。因此，日本幽门螺杆菌研究学会得出结论，所有“幽门螺杆菌感染者”均应考虑进行根除治疗，无论其有无任何基础疾病。成功根除可防止这种细菌的传播，并且最近的出版物表明，治愈幽门螺杆菌感染似乎可降低患胃癌的风险。
