Curr HIV/AIDS Rep. 2013 Dec;10(4):305-13. doi: 10.1007/s11904-013-0188-2.
Seroadaptation describes a diverse set of potentially harm-reducing behaviors that use HIV status to inform sexual decision making. Men who have sex with men (MSM) in many settings adopt these practices, but their effectiveness at preventing HIV transmission is debated. Past modeling studies have demonstrated that serosorting is only effective at preventing HIV transmission when most men accurately know their HIV status, but additional modeling is needed to address the effectiveness of broader seroadaptive behaviors. The types of information withwhichMSMmake seroadaptive decisions is expanding to include viral load, treatment status, and HIV status based on home-use tests, and recent research has begun to examine the entire seroadaptive process, from an individual's intentions to seroadapt to their behaviors to their risk of acquiring or transmitting HIV and other STIs. More research is needed to craft clear public health messages about the risks and benefits of seroadaptive practices.
血清适应描述了一系列潜在的减少伤害的行为，这些行为利用 HIV 状况来指导性行为决策。在许多环境中，与男性发生性关系的男性（MSM）采用这些做法，但它们在预防 HIV 传播方面的有效性存在争议。过去的建模研究表明，只有当大多数男性准确了解自己的 HIV 状况时，血清分类才有效预防 HIV 传播，但需要进一步建模来解决更广泛的血清适应行为的有效性。MSM 进行血清适应决策的信息类型正在扩大，包括病毒载量、治疗状况和基于家庭使用测试的 HIV 状况，最近的研究开始研究整个血清适应过程，从个人的意图到血清适应行为，再到他们感染或传播 HIV 和其他性传播感染的风险。需要进一步研究，以制定关于血清适应实践的风险和益处的明确公共卫生信息。
