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妊娠期高血压疾病:种族差异及西班牙裔悖论研究

Hypertensive disease in pregnancy: an examination of ethnic differences and the Hispanic paradox.

作者信息

Carr A, Kershaw T, Brown H, Allen T, Small M

机构信息

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Duke University, Durham, NC, USA.

出版信息

J Neonatal Perinatal Med. 2013;6(1):11-5. doi: 10.3233/NPM-1356111.

Abstract

OBJECTIVE

The "Hispanic paradox" refers to the epidemiological finding that Hispanics in the US have better health outcomes than the average population despite what their aggregate socioeconomic determinants would predict. The aim of this study was to evaluate obstetric outcomes for a multiethnic population with hypertensive diseases.

METHODS

We performed a retrospective review of parturients with hypertensive disease delivering at Duke University Medical Center. We analyzed maternal sociodemographic characteristics and ethnic differences in hypertensive disease types using Chi Square tests.

RESULTS

A total of 3,124 women delivered during a period of one year; 9% of them had hypertensive diseases in pregnancy. Gestational hypertension was more commonly diagnosed in Whites, whereas chronic hypertension and mild preeclampsia were more frequently encountered in Blacks and Hispanics respectively (Chi-square = 39.11, p < 0.001). The overall incidence of preeclampsia was less in Hispanics. However, severe preeclampsia rates were equal across groups. Hispanics were more likely to be uninsured and younger, enter prenatal care later, and least likely to complete high school. There was no significant difference in smoking or parity. Stratified analyses by ethnicity showed that the relationship between severe preeclampsia and comorbidities (intrauterine growth restriction, low birth weight, and need for admission to intensive care nursery) were least pronounced in Hispanics and strongest in Black women.

CONCLUSION

Despite similar rates of severe preeclampsia and adverse sociodemographic characteristics, Hispanic women with severe preeclampsia had better pregnancy outcomes than Black or White women with the disease.

摘要

目的

“西班牙裔悖论”指的是一项流行病学发现,即美国的西班牙裔人群尽管总体社会经济决定因素预示着相反情况,但他们的健康状况却优于普通人群。本研究的目的是评估患有高血压疾病的多民族人群的产科结局。

方法

我们对在杜克大学医学中心分娩的患有高血压疾病的产妇进行了回顾性研究。我们使用卡方检验分析了产妇的社会人口统计学特征以及高血压疾病类型中的种族差异。

结果

在一年期间共有3124名女性分娩;其中9%在孕期患有高血压疾病。白人中妊娠期高血压的诊断更为常见,而黑人中慢性高血压更为常见,西班牙裔中轻度子痫前期更为常见(卡方 = 39.11,p1<10.001)。西班牙裔中子痫前期的总体发病率较低。然而,重度子痫前期的发生率在各群体中相同。西班牙裔更有可能未参保且年龄较小1、进入产前护理的时间较晚,并且1完成高中教育的可能性最小11。吸烟或产次方面没有显著差异。按种族进行1分层分析表明,重度子痫前期与合并症(胎儿生长受限、低出生体重以及需要入住重症监护病房)之间的关系在西班牙裔中最不明显,在黑人女性中最为明显。

结论

尽管重度子痫前期的发生率以及不良社会人口统计学特征相似,但患有重度子痫前期的西班牙裔女性的妊娠结局优于患有该疾病的黑人或白人女性。 11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111在原文基础上补充完整了缺失的中文内容,使译文更符合中文表达习惯。11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111

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