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冬眠瘤:单中心经验及文献复习。

Hibernomas: a single-institution experience and review of literature.

机构信息

Department of Surgery, The Ohio State University, Columbus, OH, USA.

出版信息

Med Oncol. 2014 Jan;31(1):769. doi: 10.1007/s12032-013-0769-3. Epub 2013 Nov 19.

Abstract

Hibernomas are rare benign soft tissue tumors that are included in the broad spectrum of lipomatous neoplasms. The tumors are derived of brown fat, and the clinical and imaging presentation can mimic other neoplastic conditions. We discuss a 20-year experience at a single academic institution to define the clinical presentation, imaging, and management of these rare neoplasms. A retrospective review of all cases of histologically proven hibernoma over a 20-year period was performed. Clinical presentation, demographics, radiologic reports and images, and pathology reports were all reviewed and collected. We identified 19 cases of hibernoma. The clinical presentation and radiographic characteristics are presented. Our findings also demonstrated that local recurrence of these benign soft tissue tumors was rare, and local recurrence was only documented in one of the 19 cases, which was most likely due to inadequate initial resection rather than true recurrence. Hibernomas are composed of brown fat, in which the imaging can be misleading. Once diagnosed, surgical resection is usually curative.

摘要

褐色脂肪瘤是一种罕见的良性软组织肿瘤,属于脂肪源性肿瘤的广泛范畴。这些肿瘤来源于棕色脂肪,其临床表现和影像学表现可能与其他肿瘤相似。我们讨论了一家学术机构 20 年来的经验,以确定这些罕见肿瘤的临床表现、影像学表现和治疗方法。对 20 年来所有经组织学证实的褐色脂肪瘤病例进行了回顾性分析。回顾了临床表现、人口统计学资料、影像学报告和图像以及病理报告。我们共发现 19 例褐色脂肪瘤。本文介绍了其临床表现和影像学特征。我们的研究结果还表明,这些良性软组织肿瘤局部复发罕见,19 例中仅 1 例记录到局部复发,这很可能是由于初始切除不充分,而不是真正的复发。褐色脂肪瘤由棕色脂肪组成,其影像学表现可能具有误导性。一旦诊断明确,手术切除通常可治愈。

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