Department of Chemistry and Biochemistry, University of Delaware, 19716, Newark, DE.
J Am Soc Mass Spectrom. 1990 Sep;1(5):397-404. doi: 10.1016/1044-0305(90)85020-M.
The relative molar sensitivities for a number of compounds having a variety of functional groups were obtained in gas chromatography electron ionization mass spectrometry. Comparable results were obtained with a quadrupole and with a magnetic mass spectrometer. The present relative molar sensitivities are in good agreement with relative ionization cross sections obtained by different techniques and different instruments for a variety of compounds with molecular weights below about 200 u. For compounds of higher molecular weight, the present experimental sensitivities are significantly larger than estimates extrapolated from earlier data. The relatively molar sensitivities correlate well with molecular polarizability.
采用气相色谱-电子电离质谱法获得了具有各种官能团的许多化合物的相对摩尔灵敏度。在四极杆和磁场质谱仪中均得到了类似的结果。目前的相对摩尔灵敏度与通过不同技术和不同仪器获得的各种分子量低于约 200 u 的化合物的相对电离截面很好地吻合。对于分子量较高的化合物，目前的实验灵敏度明显大于从早期数据推断出的估计值。相对摩尔灵敏度与分子极化率有很好的相关性。
