Polese Francesco, Capunzo M
Dept. of Business Studies (Management & Information Technology), University of Salerno, Italy - (
Transl Med UniSa. 2013 May 6;6:29-34. eCollection 2013.
Scope of Translational Medicine is to speed the development of new compounds of medical protocols and/or treatments to improve patient's quality of life. Translational medicine represents the synergy between epidemiology, basic research and clinical trials, and is based upon Innovation Management and Research Development in medicine. Being the speed and progression up to the patient a key issue of Translational Medicine, the innovation process ought to be pursued according to rigorous protocols embedded on a research development path capable of decreasing the lead time at the most. Translational Medicine represents a goal to be pursued by all involved actors, from academic researchers to clinicians, patients and others than can be seen as a network of co-creating actors engaged for the ultimate patient benefit. To underpin Translational Medicine advantages and determinants, the paper approaches the issue by adopting a systems thinking perspective, capable of highlighting the key issues to be considered.
转化医学的范围是加快新的医学方案和/或治疗化合物的开发,以提高患者的生活质量。转化医学代表了流行病学、基础研究和临床试验之间的协同作用,并且基于医学中的创新管理和研究发展。由于速度和向患者推进是转化医学的关键问题,创新过程应根据严格的方案来进行,这些方案嵌入在能够最大程度缩短前置时间的研究发展路径中。转化医学是所有相关参与者(从学术研究人员到临床医生、患者以及其他可被视为共同创造的参与者网络)都应追求的目标,其目的是最终使患者受益。为了支持转化医学的优势和决定因素,本文采用系统思维视角来探讨这个问题,这种视角能够突出需要考虑的关键问题。