Battaglia Manuela, Furlong Pat, Wulffraat Nico Martinus, Bellutti Enders Felicitas
Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Parent Project Muscular Dystrophy, Hackensack, NJ, United States.
Front Med (Lausanne). 2019 May 21;6:110. doi: 10.3389/fmed.2019.00110. eCollection 2019.
Translational medicine works through the definition of unmet medical needs, their understanding and final resolution. In this complex and multi-disciplinary process patients have always been regarded as "end-users" or no more than "data provider." Considering that the translational practice is nowadays highly inefficient (i.e., large intellectual and economical resources are wasted with limited impact on people health) here we propose to reverse the process: start from patients, engage them, and keep them at the center. A new partnership needs to be formed between the patients and the health care professionals, as well as the treating physicians, to make the most out of the current "health resources." New patient-centric approaches are emerging but they remain isolated phenomena often difficult to implement. Here-with this perspective-we aim at thinking differently and learning from new experiences. We will provide some successful examples of change, and we will discuss new approaches to create a radical change in the way translational medicine is managed and how this would significantly impact people health and health care systems.
转化医学通过定义未满足的医疗需求、理解这些需求并最终解决它们来发挥作用。在这个复杂且多学科的过程中，患者一直被视为“终端用户”或仅仅是“数据提供者”。鉴于如今的转化实践效率极低（即大量的智力和经济资源被浪费，而对人们健康的影响有限），我们在此提议扭转这一过程：从患者出发，让他们参与进来，并将他们置于中心位置。患者与医疗保健专业人员以及治疗医生之间需要建立一种新的伙伴关系，以便充分利用当前的“健康资源”。以患者为中心的新方法正在涌现，但它们仍然是孤立的现象，往往难以实施。基于此观点，我们旨在换一种思维方式并从新经验中学习。我们将提供一些成功的变革案例，并讨论新的方法，以在转化医学的管理方式上带来根本性变革，以及这将如何对人们的健康和医疗保健系统产生重大影响。
