Chinawa Josephat M, Eze John C, Obi Ikechukwu, Arodiwe Ijeoma, Ujunwa Fortune, Daberechi Adiele K, Obu Herbert A
Department of Paediatrics, University of Nigeria/Teaching Hospital, Enugu, Nigeria.
BMC Res Notes. 2013 Nov 19;6:475. doi: 10.1186/1756-0500-6-475.
The objective of this study was to determine the pattern of congenital cardiac disease among children attending UNTH, Enugu, Nigeria. The nature of these abnormalities and the outcome were also considered. The exact etiology is unknown but genetic and environmental factors tend to be implicated. The difference in the pattern obtained worldwide and few studies in Nigeria could be due to genetic, environmental, socioeconomic, or ethnic origin.
A retrospective analysis of discharged cases in which a review of the cases of all children attending children outpatient clinics including cardiology clinic of the University of Nigeria Teaching Hospital (UNTH), Enugu over a five year period (January 2007-June 2012) was undertaken. All the children presenting with cardiac anomalies were included in the study and the cases were investigated using ECG, X-ray and echocardiography studies.
A total of 31,795 children attended the children outpatient clinics of the hospital over the study period. Of these, seventy one (71) had cardiac diseases. The overall prevalence of cardiac disease is 0.22%. The commonest symptoms were breathlessness, failure to thrive and cyanosis. Almost all types of congenital detects were represented, the commonest being isolated ventricular septal detect (VSD), followed by tetralogy of Fallot. One of these cardiac anomalies presented with Downs's syndrome and another with VACTERAL association.
The results of this study show that 0.22% per cent of children who attended UNTH in Enugu State had congenital cardiac abnormalities and the commonest forms seen were those with VSD.
本研究旨在确定尼日利亚埃努古大学教学医院(UNTH)就诊儿童的先天性心脏病模式。还考虑了这些异常的性质及结果。确切病因尚不清楚,但往往涉及遗传和环境因素。全球范围内所获模式的差异以及尼日利亚的少数研究结果可能归因于遗传、环境、社会经济或种族起源。
对出院病例进行回顾性分析,对尼日利亚大学教学医院(UNTH)埃努古分院儿童门诊(包括心脏病门诊)五年期间(2007年1月至2012年6月)所有儿童病例进行了审查。所有出现心脏异常的儿童均纳入研究,病例通过心电图、X线和超声心动图检查进行调查。
在研究期间,共有31,795名儿童到该医院儿童门诊就诊。其中,71名患有心脏病。心脏病的总体患病率为0.22%。最常见的症状是呼吸急促、发育不良和发绀。几乎所有类型的先天性缺陷均有体现,最常见的是孤立性室间隔缺损(VSD),其次是法洛四联症。这些心脏异常病例中,1例伴有唐氏综合征,另1例伴有VACTERAL综合征。
本研究结果表明,在埃努古州UNTH就诊的儿童中,0.22%患有先天性心脏异常,最常见的类型是VSD。