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小球腊梅菌株对小藜碱生物转化生成 5-甲酰小藜碱。

Biotransformation of ellipticine into 5-formyl ellipticine by Choisya ternata strains.

机构信息

Faculté de Pharmacie, Laboratoire de Biotechnologie Végétale, F-37032, Tours, France.

出版信息

Plant Cell Rep. 1984 Oct;3(5):203-5. doi: 10.1007/BF00270201.

Abstract

Sixteen Choisya ternata strains of same genotypic origin were examined for their capacities to biotransform ellipticine. Four strains were able to convert the drug into 5-formylellipticine with good yields. The reaction occurred only in agar medium and was different from ellipticine bioconversion by microorganisms or mammals.

摘要

对 16 株来源相同基因型的蜡梅进行了生物转化椭圆梅素的能力检测。其中 4 株菌株能够以较高的产率将药物转化为 5-甲酰基椭圆梅素。该反应仅在琼脂培养基中发生,与微生物或哺乳动物的椭圆梅素生物转化不同。

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