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Immunologic histamine release from isolated human basophils during specific immunotherapy.

作者信息

Chyrek-Borowska S, Kuczewska B, Rogalewska A, Hofman J

出版信息

Agents Actions. 1986 Apr;18(1-2):176-7. doi: 10.1007/BF01988014.

DOI:10.1007/BF01988014
PMID:2425578
Abstract

Anti-IgE- and antigen-induced histamine release from basophils isolated from 20 atopic patients sensitive to grass pollen allergens was evaluated. The studies were made before and after short-term immunotherapy with Pollinex. It was shown, that after hyposensitization a significant decrease on anti-IgE and specific antigen-induced histamine release from basophils occurs.

摘要

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Immunologic histamine release from isolated human basophils during specific immunotherapy.
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Hyposensitization to allergic reaction in rDer f 2-sensitized mice by the intranasal administration of a mutant of rDer f 2, C8/119S.通过鼻内给予rDer f 2的突变体C8/119S对rDer f 2致敏小鼠的过敏反应进行减敏。
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本文引用的文献

1
A method for the fluorometric assay of histamine in tissues.一种用于组织中组胺荧光测定的方法。
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2
Immunotherapy.
Prog Allergy. 1982;32:318-46. doi: 10.1159/000318291.
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Clinical and immunologic aspects of allergen-specific immunotherapy in patients with seasonal allergic rhinitis and/or allergic asthma.季节性变应性鼻炎和/或变应性哮喘患者变应原特异性免疫治疗的临床和免疫学方面
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In vitro standardization of basophil histamine release.
Allergy. 1980 Apr;35(3):238-40. doi: 10.1111/j.1398-9995.1980.tb01760.x.
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Basophil leucocyte separation from human peripheral blood: a technique for their isolation in high purity and high yield.从人外周血中分离嗜碱性白细胞：一种高纯度、高产量分离嗜碱性白细胞的技术。
Clin Allergy. 1972 Sep;2(3):205-12. doi: 10.1111/j.1365-2222.1972.tb01284.x.
6
Diagnostic tests in ragweed hay fever. A comparison of direct skin tests, IgE antibody measurements, and basophil histamine release.豚草花粉热的诊断测试。直接皮肤试验、IgE抗体测量和嗜碱性粒细胞组胺释放的比较。
J Allergy Clin Immunol. 1973 Oct;52(4):210-24. doi: 10.1016/0091-6749(73)90059-6.
7
A simplified method for measuring basophil histamine release and blocking antibodies in hay fever patients. Basophil histamine content and cell preservation.
Acta Allergol. 1977 Jun;32(3):170-82. doi: 10.1111/j.1398-9995.1977.tb01347.x.