Deards M J, Standring R, Moran D M
Int Arch Allergy Appl Immunol. 1986;80(3):253-7. doi: 10.1159/000234061.
IgG antibody responses, induced by individual temperate grass pollen allergens in atopic subjects, have been studied by an SDS-PAGE immunoprecipitation technique. These were shown to be of a complex nature and variable between individuals. Profiles obtained with serum and nasal secretions from the same individual were qualitatively similar. Immunotherapy with a glutaraldehyde-modified grass pollen extract, Pollinex, increased the level of specific IgG to three clinically significant grass pollen allergens but did not markedly change the overall pattern of response.
通过SDS-PAGE免疫沉淀技术，研究了特应性个体中由单个温带草花粉过敏原诱导的IgG抗体反应。结果显示这些反应性质复杂，个体间存在差异。同一受试者血清和鼻分泌物的检测结果在定性上相似。用戊二醛修饰的草花粉提取物Pollinex进行免疫治疗，可使三种临床上重要的草花粉过敏原的特异性IgG水平升高，但并未显著改变总体反应模式。
