Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.
Int J Gynecol Cancer. 2013 Oct;23(8):1411-6. doi: 10.1097/IGC.0b013e3182a580d3.
To analyze the accuracy of magnetic resonance imaging (MRI) and intraoperative frozen sectioning (IFS) for predicting the low- and high-risk patients and risk factors associated with lymph node (LN) metastasis in patients with surgically staged endometrial cancer.
The medical records of 175 patients with endometrial cancer who underwent comprehensive surgical staging including pelvic and para-aortic LN dissection between January 2008 and July 2011 were retrospectively analyzed. Results of MRI and IFS of the uterus for the evaluation of risk factors were correlated with final pathology.
Our results showed a high specificity and negative predictive value of MRI and IFS for the evaluation of myometrial invasion and cervical stromal invasion. Of the 41 patients identified as low risk by both MRI and IFS, none had pelvic or para-aortic LN metastases in the final pathology.
The results indicate that MRI and IFS may be useful for the evaluation of risk factors associated with LN metastasis in patients with endometrial cancer. Magnetic resonance imaging and IFS can be used to accurately identify low-risk patients who do not need comprehensive surgical staging and may prevent unnecessary lymphadenectomy.
分析磁共振成像（MRI）和术中冷冻切片（IFS）在预测接受手术分期的子宫内膜癌患者中与淋巴结（LN）转移相关的低危和高危患者及危险因素的准确性。
回顾性分析了 2008 年 1 月至 2011 年 7 月期间接受包括盆腔和主动脉旁淋巴结清扫术在内的全面手术分期的 175 例子宫内膜癌患者的病历。子宫 MRI 和 IFS 评估危险因素的结果与最终病理相关。
我们的结果表明，MRI 和 IFS 对评估肌层浸润和宫颈间质浸润具有较高的特异性和阴性预测值。在通过 MRI 和 IFS 均被确定为低危的 41 例患者中，最终病理均未发现盆腔或主动脉旁 LN 转移。
结果表明，MRI 和 IFS 可能有助于评估子宫内膜癌患者与 LN 转移相关的危险因素。MRI 和 IFS 可用于准确识别无需全面手术分期的低危患者，并可能预防不必要的淋巴结切除术。
