风疹E1糖蛋白的免疫学特性。简要报告。
Immunological characterisation of the rubella E 1 glycoprotein. Brief report.
作者信息
Ho-Terry L, Terry G M, Cohen A, Londesborough P
出版信息
Arch Virol. 1986;90(1-2):145-52. doi: 10.1007/BF01314152.
PMID:2425779
Abstract
Three epitopes have been identified on rubella virion envelope polypeptide E 1 using monoclonal antibodies. Antibodies to two of the epitopes, E 1EP1 and E 1EP2, show both haemagglutination inhibition and neutralization activities whereas antibodies to the remaining epitope, E 1EP3, show neutralizing activity only.
摘要
利用单克隆抗体已在风疹病毒粒子包膜多肽E1上鉴定出三个表位。针对其中两个表位E1EP1和E1EP2的抗体同时具有血凝抑制和中和活性，而针对其余表位E1EP3的抗体仅具有中和活性。
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